Literature DB >> 4791487

Pharmacology of gentamicin in the biliary tract of humans.

J Mendelson, J Portnoy, H Sigman.   

Abstract

Serum and biliary tract levels of gentamicin were determined in a large series of patients. In only 17.7% of subjects were therapeutic serum levels achieved, even though recommended doses of gentamicin were administered. Therapeutic bile gentamicin levels were reached in only some of the patients with therapeutic serum levels.

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Year:  1973        PMID： 4791487      PMCID： PMC444591          DOI： 10.1128/AAC.4.5.538

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  5 in total

1.  Recent microbiological studies with gentamicin.

Authors:  J A Waitz; M J Weinstein
Journal:  J Infect Dis       Date:  1969 Apr-May       Impact factor: 5.226

2.  Gentamicin levels in the human biliary tract.

Authors:  H A Pitt; R B Roberts; W D Johnson
Journal:  J Infect Dis       Date:  1973-03       Impact factor: 5.226

3.  Gentamicin and ampicillin in human bile.

Authors:  T Smithivas; P J Hyams; J J Rahal
Journal:  J Infect Dis       Date:  1971-12       Impact factor: 5.226

4.  Pharmacology of gentamicin in man.

Authors:  L J Riff; G G Jackson
Journal:  J Infect Dis       Date:  1971-12       Impact factor: 5.226

5.  Rapid microassay for circulating nephrotoxic antibiotics.

Authors:  L D Sabath; J I Casey; P A Ruch; L L Stumpf; M Finland
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1970
  5 in total
  7 in total

1.  Aminoglycoside therapy: current and prospective uses.

Authors:  J E Leggett
Journal:  Tex Heart Inst J       Date:  1990

2.  Safety of the bolus administration of gentamicin.

Authors:  J Mendelson; J Portnoy; V Dick; M Black
Journal:  Antimicrob Agents Chemother       Date:  1976-04       Impact factor: 5.191

3.  Pharmacokinetics of intramuscularly administered aminosidine in healthy subjects.

Authors:  T P Kanyok; A D Killian; K A Rodvold; L H Danziger
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

4.  Kill kinetics and regrowth patterns of Escherichia coli exposed to gentamicin concentration-time profiles simulating in vivo bolus and infusion dosing.

Authors:  E B Bastone; S C Li; L L Ioannides-Demos; W J Spicer; A J McLean
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

5.  Cefoperazone compared with ampicillin plus tobramycin for severe biliary tract infections.

Authors:  M G Bergeron; J Mendelson; G K Harding; L Mandell; I W Fong; A Rachlis; R Chan; S Biron; R Feld; N B Segal
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

Review 6.  Why monitor serum levels of gentamicin?

Authors:  M Barza; M Lauermann
Journal:  Clin Pharmacokinet       Date:  1978 May-Jun       Impact factor: 6.447

7.  Biliary tract excretion of cefazolin, cephalothin, and cephaloridine in the presence of biliary tract disease.

Authors:  K R Ratzan; C Ruiz; G L Irvin
Journal:  Antimicrob Agents Chemother       Date:  1974-10       Impact factor: 5.191
  7 in total

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