Literature DB >> 4791479

Separation and detection of tetracyclines by high-speed liquid chromatography.

A G Butterfield, D W Hughes, N J Pound, W L Wilson.   

Abstract

The high-speed liquid chromatographic behavior of 15 tetracyclines on anion- and cation-exchange columns is described and illustrated by typical separations of a number of tetracycline derivatives on several systems, as well as by the resolution of tetracycline from its degradation products epi-, epianhydro-, and anhydrotetracycline. These serve as a basis for a rapid, convenient, and precise method for the direct detection of the tetracycline antibiotics and their degradation products.

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Year:  1973        PMID: 4791479      PMCID: PMC444497          DOI: 10.1128/AAC.4.1.11

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  23 in total

1.  Tetracyclines I. Separation and examination by thin-layer chromatography.

Authors:  P P Ascione; J B Zagar; G P Chrekian
Journal:  J Pharm Sci       Date:  1967-11       Impact factor: 3.534

2.  Quantitative determination by thin-layer chromatography of anhydrotetracyclines in degraded tetracycline tablets.

Authors:  D L Simmons; H S Woo; C M Koorengevel; P Seers
Journal:  J Pharm Sci       Date:  1966-11       Impact factor: 3.534

3.  Chromatographic methods for the determination of tetracycline by-products.

Authors:  L Lodi; G Meinardi; E Rossi
Journal:  Farmaco Prat       Date:  1969-12

Review 4.  Applications of thin-layer chromatography in pharmaceutical analyses.

Authors:  J P Comer; I Comer
Journal:  J Pharm Sci       Date:  1967-04       Impact factor: 3.534

5.  Determination of epitetracycline and chlortetracycline in tetracycline by quantitative thin-layer chromatography.

Authors:  I C Dijkhuis; M R Brommet
Journal:  J Pharm Sci       Date:  1970-04       Impact factor: 3.534

6.  A fluorometric method of analysis for tetracycline.

Authors:  R G Kelly; L M Peets; K D Hoyt
Journal:  Anal Biochem       Date:  1969-04-04       Impact factor: 3.365

7.  Determination of tetracycline antibiotics by alternating-current polarography.

Authors:  M E Caplis; H S Ragheb; E D Schall
Journal:  J Pharm Sci       Date:  1965-05       Impact factor: 3.534

8.  Quantitative analysis of anhydrotetracycline on microcrystalline cellulose.

Authors:  D L Simmons; C K Koorengevel; R Kubelka; P Seers
Journal:  J Pharm Sci       Date:  1966-02       Impact factor: 3.534

9.  Application of absorbance ratios to analysis of pharmaceuticals. V. Analysis of tetracycline hydrochloride in presence of anhydrotetracycline and epianhydrotetracycline.

Authors:  M Pernarowski; R O Searl; J Naylor
Journal:  J Pharm Sci       Date:  1969-04       Impact factor: 3.534

10.  Simultaneous separation and quantitative determination of tetracycline, anhydrotetracycline, 4-epitetracycline, and 4-epi-anhydrotetracycline in degraded tetracyclines by thin-layer chromatography.

Authors:  A Alvarez Fernandez; V Torre Noceda; E Sanchez Carrera
Journal:  J Pharm Sci       Date:  1969-04       Impact factor: 3.534

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