Literature DB >> 4790571

Effect of hepatic insufficiency on 5-fluorocytosine concentrations in serum.

E R Block.   

Abstract

Hepatic function failed to influence serum concentrations of the antifungal agent 5-fluorocytosine when the drug was given intravenously to rabbits with CCl(4)-induced hepatic insufficiency or orally to a patient with postnecrotic cirrhosis.

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Year:  1973        PMID： 4790571      PMCID： PMC444376          DOI： 10.1128/AAC.3.1.141

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  Hepatic failure as a manifestation of cryptococcosis.

Authors:  S M SABESIN; H J FALLON; V T ANDRIOLE
Journal:  Arch Intern Med       Date:  1963-05

2.  5-fluorocytosine in the treatment of mycotic infections.

Authors:  A G Vandevelde; A A Mauceri; J E Johnson
Journal:  Ann Intern Med       Date:  1972-07       Impact factor: 25.391

3.  Pharmacological studies with 5-fluorocytosine.

Authors:  E R Block; J E Bennett
Journal:  Antimicrob Agents Chemother       Date:  1972-06       Impact factor: 5.191

4.  The metabolism of 5-fluorocytosine-2-14-C and of cytosine-14-C in the rat and the disposition of 5-fluorocytosine-2-14-C in man.

Authors:  B A Koechlin; F Rubio; S Palmer; T Gabriel; R Duschinsky
Journal:  Biochem Pharmacol       Date:  1966-04       Impact factor: 5.858
  4 in total
  2 in total

Review 1.  Pharmacokinetics of antifungal drugs: practical implications for optimized treatment of patients.

Authors:  Romuald Bellmann; Piotr Smuszkiewicz
Journal:  Infection       Date:  2017-07-12       Impact factor: 3.553

Review 2.  Clinical pharmacokinetics of systemic antifungal drugs.

Authors:  T K Daneshmend; D W Warnock
Journal:  Clin Pharmacokinet       Date:  1983 Jan-Feb       Impact factor: 6.447
  2 in total

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