| Literature DB >> 4787521 |
Abstract
In hearts of newborn mice, maintained in organ culture in an in vitro environment, noradrenaline levels were reduced after 24 h but subsequently recovered, reaching at three days values significantly greater than those found at birth. The increased synthesis of noradrenaline was blocked by the inhibitor of tyrosine hydroxylase, alpha-methyl tyrosine methyl ester. The site and control of noradrenaline biosynthesis in cultured newborn hearts are discussed.Entities:
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Year: 1973 PMID： 4787521 PMCID： PMC1776440 DOI： 10.1111/j.1476-5381.1973.tb08276.x
Source DB: PubMed Journal: Br J Pharmacol ISSN： 0007-1188 Impact factor: 8.739