Literature DB >> 477897

alpha-Mercaptopropionyl-glycine influence on the in vitro proliferative response of human lymphocytes.

G Semenzato, A Pezzutto, G Amadori, R Raimondi, G Gasparotto.   

Abstract

The effect of alpha-mercaptopropinyl-glycine on the in vitro proliferative response of healthy subjects' lymphocytes was studied. Low doses of the drug enhanced spontaneous lymphocyte blastigenesis but had no effect on the PHA-induced blastic response. With increasing concentrations of alpha-mercaptopropionyl-glycine inhibition of 3H-thymidine incorporation was found in unstimulated as well as in PHA stimulated lymphocytes.

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Year:  1979        PMID： 477897     DOI： 10.1007/bf01949972

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  9 in total

1.  Effect of penicillamine on cystinuria.

Authors:  J C CRAWHALL; E F SCOWEN; R W WATTS
Journal:  Br Med J       Date:  1963-03-02

2.  Penicillamine and vitamin B6 interrelationships in the rat.

Authors:  J G HEDDLE; E W McHENRY; G H BEATON
Journal:  Can J Biochem Physiol       Date:  1963-05

3.  Active E rosette formation by human lymphoblasts.

Authors:  G Semenzato; G Amadori; P Sarasin; G Gasparotto
Journal:  Immunology       Date:  1978-04       Impact factor: 7.397

4.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

5.  Treatment of cystinuria with alpha-mercaptopropionylglycine: a preliminary report with some notes on column chromatography of mercaptans.

Authors:  J S King
Journal:  Proc Soc Exp Biol Med       Date:  1968-12

6.  Spontaneous lymphocyte transformation in chronic lymphocytic leukaemia.

Authors:  G Semenzato; G Amadori; F Tosato; G Gasparotto
Journal:  Clin Exp Immunol       Date:  1977-06       Impact factor: 4.330

7.  Effects of therapeutically useful thiols (DL-penicillamine and alpha-mercaptopropionylglycine) on immunoglobulins.

Authors:  G Virella; M F Lopes-Virella
Journal:  Clin Exp Immunol       Date:  1970-07       Impact factor: 4.330

8.  D-penicillamine and macrophages: modulation of lymphocyte transformation by concanavalin A.

Authors:  L Binderup; E Bramm; E Arrigoni-Martelli
Journal:  Scand J Immunol       Date:  1978-04       Impact factor: 3.487

9.  In vitro induction of polyclonal killer T cells with 2-mercaptoethanol and the essential role of macrophages in this process.

Authors:  T Igarashi; M Okada; T Kishimoto; Y Yamamura
Journal:  J Immunol       Date:  1977-05       Impact factor: 5.422
  9 in total

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