Literature DB >> 477888

Activation by S-adenosylhomocysteine of norepinephrine and serotonin in vitro uptake in synaptosomal preparations from rat brain.

P Fonlupt, M Roche, L Cronenberger, H Pacheco.   

Abstract

S-Adenosylhomocysteine (10(-7)-10(-5) M) activated norepinephrine (NE) and serotonin (5HT) in vitro uptake in synaptosomal preparations from rat brain, but did not affect dopamine (DA) uptake. When administered to rats (7 mg/kg i.p.), it has the same effect on in vitro NE and 5HT uptake. It did not affect NE and 5HT release.

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Year:  1979        PMID： 477888     DOI： 10.1007/bf01949959

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  7 in total

Review 1.  Biological transmethylation involving S-adenosylmethionine: development of assay methods and implications for neuropsychiatry.

Authors:  R J Baldessarini
Journal:  Int Rev Neurobiol       Date:  1975       Impact factor: 3.230

2.  Effect of S-adenosylhomocysteine and S-tubercidinylhomocysteine on transfer ribonucleic acid methylation in phytohemagglutinin-stimulated lymphocytes.

Authors:  C D Chang; J K Coward
Journal:  Mol Pharmacol       Date:  1975-11       Impact factor: 4.436

3.  Calcium-dependent release of radiolabeled catecholamines and serotonin from rat brain synaptosomes in a superfusion system.

Authors:  A H Mulder; W B van den Berg; J C Stoof
Journal:  Brain Res       Date:  1975-12-05       Impact factor: 3.252

4.  Uptake and binding of catecholamines. Effect of diphenylhydantoin and a new mechanism of action.

Authors:  M G Hadfield
Journal:  Arch Neurol       Date:  1972-01

5.  Regional differences in H3-norepinephrine and H3-dopamine uptake into rat brain homogenates.

Authors:  S H Snyder; J T Coyle
Journal:  J Pharmacol Exp Ther       Date:  1969-01       Impact factor: 4.030

6.  Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.

Authors:  J Glowinski; L L Iversen
Journal:  J Neurochem       Date:  1966-08       Impact factor: 5.372

7.  S-Adenosyl-L-homocysteine in brain : Regional concentrations, catabolism, and the effects of methionine sulfoximine.

Authors:  R A Schatz; C R Vunnam; O Z Sellinger
Journal:  Neurochem Res       Date:  1977-02       Impact factor: 3.996
  7 in total
  1 in total

1.  Down-regulation of S-adenosylhomocysteine hydrolase in the active methyl transfer system in the brain of genetically epileptic El mice.

Authors:  O Ohmori; H Hirano; T Ono; K Abe; T Mita
Journal:  Neurochem Res       Date:  1996-10       Impact factor: 3.996
  1 in total

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