Literature DB >> 477843

Disparate Na+-requirement of taurocholate and indocyanine green uptake by isolated hepatocytes.

E Minder, G Paumgartner.   

Abstract

Uptake of both taurocholate and indocyanine green (ICG) by isolated rat hepatocytes was saturable and obeyed Michaelis-Menten kinetics. Only uptake of taurocholate exhibited Na+-dependence, a phenomenon compatible with active membrane transport. These findings suggest that the mechanisms responsible for hepatocellular uptake of bile acids and anionic dyes differ fundamentally.

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Year:  1979        PMID: 477843     DOI: 10.1007/bf01955131

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  14 in total

1.  Different pathways for hepatic uptake of taurocholate and indocyanine green.

Authors:  G Paumgartner; J Reichen
Journal:  Experientia       Date:  1975-03-15

2.  The handling of indocyanine green by the liver.

Authors:  G Paumgartner
Journal:  Schweiz Med Wochenschr       Date:  1975

3.  INITIAL DISTRIBUTION AND RATE OF UPTAKE OF SULFOBROMOPHTHALEIN IN THE LIVER.

Authors:  C A GORESKY
Journal:  Am J Physiol       Date:  1964-07

4.  Statistical estimations in enzyme kinetics.

Authors:  G N WILKINSON
Journal:  Biochem J       Date:  1961-08       Impact factor: 3.857

5.  Uptake of taurocholic acid into isolated rat-liver cells.

Authors:  L R Schwarz; R Burr; M Schwenk; E Pfaff; H Greim
Journal:  Eur J Biochem       Date:  1975-07-15

6.  Effect of albumin on bile acid uptake by isolated rat hepatocytes. Is there a common bile acid carrier?

Authors:  M S Anwer; R Kroker; D Hegner
Journal:  Biochem Biophys Res Commun       Date:  1976-11-08       Impact factor: 3.575

7.  Kinetics of hepatic uptake of unconjugated bilirubin.

Authors:  G Paumgartner; J Reichen
Journal:  Clin Sci Mol Med       Date:  1976-08

Review 8.  Coupled transport of sodium and organic solutes.

Authors:  S G Schultz; P F Curran
Journal:  Physiol Rev       Date:  1970-10       Impact factor: 37.312

9.  Uptake of bile acids by perfused rat liver.

Authors:  J Reichen; G Paumgartner
Journal:  Am J Physiol       Date:  1976-09

10.  Hepatic organic anion uptake in the rat.

Authors:  B F Scharschmidt; J G Waggoner; P D Berk
Journal:  J Clin Invest       Date:  1975-11       Impact factor: 14.808

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  2 in total

1.  Phenolsulfonphthalein (phenol red) metabolism in primary monolayer cultures of adult rat hepatocytes.

Authors:  J L Driscoll; N T Hayner; R Williams-Holland; G Spies-Karotkin; P M Galletti; H O Jauregui
Journal:  In Vitro       Date:  1982-10

2.  Common properties of hepatocellular uptake of cholate, iodipamide and antamanide, as distinct from the uptake of bromosulfophthalein.

Authors:  E Petzinger; C Joppen; M Frimmer
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-03       Impact factor: 3.000

  2 in total

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