Literature DB >> 4778282

Isolation and characterization of a glycoprotein from human colostrum.

J H Nichols, A Bezkorovainy.   

Abstract

A glycoprotein was isolated from the M-1 acid glycoprotein fraction of human colostrum. It had a molecular weight of 31200 and contained 27% galactose, 21.7% hexosamine, 8.0% fucose and 10.8% sialic acid by weight. The glycoprotein had no absorption maxima in the 240-300nm region, and was virtually free of ABH(O) and M and N blood-group activity. Alkaline borohydride cleavage of the glycoprotein resulted predominantly in the destruction of threonine and galactosamine.

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Year:  1973        PMID: 4778282      PMCID: PMC1165907          DOI: 10.1042/bj1350875

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  21 in total

1.  DISC ELECTROPHORESIS. II. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS.

Authors:  B J DAVIS
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  A modified colorimetric method for the estimation of N-acetylamino sugars.

Authors:  J L REISSIG; J L STORMINGER; L F LELOIR
Journal:  J Biol Chem       Date:  1955-12       Impact factor: 5.157

3.  Pentose-rich glycoprotein from bovine vitreous body. I. Isolation and partial characterization.

Authors:  W S Allen; A H Wardi
Journal:  Biochim Biophys Acta       Date:  1973-01-24

4.  Isolation and properties of human blood-group NN and meconium-Vg antigens.

Authors:  G F Springer; Y Nagai; H Tegtmeyer
Journal:  Biochemistry       Date:  1966-10       Impact factor: 3.162

5.  The peptide moiety of human-blood-group active glycoproteins associated with the ABO and Lewis groups.

Authors:  A S Donald; J M Creeth; W T Morgan; W M Watkins
Journal:  Biochem J       Date:  1969-10       Impact factor: 3.857

6.  Determination of hexosaminitols by ion-exchange chromatography and its application to alkali-labile glycosidic linkages in glycoproteins.

Authors:  P Weber; R J Winzler
Journal:  Arch Biochem Biophys       Date:  1969-02       Impact factor: 4.013

7.  Biologically active glycopeptides in human colostrum.

Authors:  S Hirano; H Hayashi; T Terabayashi; K Onodera; S Iseki
Journal:  J Biochem       Date:  1968-10       Impact factor: 3.387

8.  Comparative study of the acid glycoproteins isolated from bovine serum, colostrum, and milk whey.

Authors:  A Bezkorovainy
Journal:  Arch Biochem Biophys       Date:  1965-06       Impact factor: 4.013

9.  Enzymatic synthesis of the protein-hexosamine linkage in sheep submaxillary mucin.

Authors:  E J McGuire; S Roseman
Journal:  J Biol Chem       Date:  1967-08-25       Impact factor: 5.157

10.  Physical and chemical properties of bovine milk and colostrum whey M-1 glycoproteins.

Authors:  A Bezkorovainy
Journal:  J Dairy Sci       Date:  1967-09       Impact factor: 4.034

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  1 in total

1.  Chemical and physical properties of the human urinary glycoprotein with gastric antisecretory activity.

Authors:  G Lugaro; P Pasta; M M Casellato; G Mazzola; G Carrea
Journal:  Biochem J       Date:  1976-03-01       Impact factor: 3.857

  1 in total

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