Literature DB >> 4777715

Effects of a new tetrahydroisoquinoline (NC-7197) in experimental cardiogenic shock.

M F Ghani, R M Hopkins, J R Smith, D R VanDeripe.   

Abstract

Intravenous administration of 1.0 mg/kg of NC-7197 to open and closed-chest anaesthetized dogs immediately after induction of cardiogenic shock by miliary coronary embolization resulted in significant haemodynamic improvement and prolonged survival. These results suggest that NC-7197 may prove to be valuable in the initial management of myocardial infarction complicated by hypotension and shock.

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Year:  1973        PMID: 4777715      PMCID: PMC1776492          DOI: 10.1111/j.1476-5381.1973.tb17266.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  8 in total

1.  Protracted shock in the closed-chest dog following coronary embolization with graded microspheres.

Authors:  C M AGRESS; M J ROSENBERG; H I JACOBS; M J BINDER; A SCHNEIDERMAN; W G CLARK
Journal:  Am J Physiol       Date:  1952-09

2.  Adrenergic blocking and cardiovascular effects of a new N-substituted tetrahydroisoquinoline (NC 7197).

Authors:  P J Privitera; T Blickenstaff; T E Gaffney; S Mohammed
Journal:  J Pharmacol Exp Ther       Date:  1971-03       Impact factor: 4.030

3.  Phentolamine for vasodilator treatment of severe heart-failure.

Authors:  P A Majid; B Sharma; S H Taylor
Journal:  Lancet       Date:  1971-10-02       Impact factor: 79.321

4.  The treatment of cardiogenic shock. VI. The search for an ideal drug.

Authors:  L I Goldberg
Journal:  Am Heart J       Date:  1968-03       Impact factor: 4.749

5.  Chlorpromazine in the treatment of cardiogenic shock.

Authors:  S J Gulotta
Journal:  Am Heart J       Date:  1970-10       Impact factor: 4.749

6.  Comparison of early hemodynamic phenomena in three forms of shock in dogs.

Authors:  T E Bynum; G F Brobmann; E D Jacobson; C K Su
Journal:  Proc Soc Exp Biol Med       Date:  1971-02

7.  Hemodynamic effects of an isoquinoline derivative in the treatment of hemorrhagic shock.

Authors:  S I Kim; T P Nassos; W C Shoemaker
Journal:  J Surg Res       Date:  1971-08       Impact factor: 2.192

8.  The treatment of cardiogenic shock. II. The use of pressor agents in the treatment of cardiogenic shock.

Authors:  L A Kuhn
Journal:  Am Heart J       Date:  1967-11       Impact factor: 4.749

  8 in total

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