Literature DB >> 4770400

The metabolic fate of the methylnitroimidazole moiety of azathioprine in the rat.

P De MIRANDA, L M Beacham, T H Creagh, G B Elion.   

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Year:  1973        PMID: 4770400

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN: 0022-3565            Impact factor:   4.030


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  7 in total

1.  Nobel lecture in physiology or medicine--1988. The purine path to chemotherapy.

Authors:  G B Elion
Journal:  In Vitro Cell Dev Biol       Date:  1989-04

2.  Effects of azathioprine on the human mixed lymphocyte reaction (MLR).

Authors:  S A Al-Safi; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1983-02       Impact factor: 4.335

3.  Sequential group trial to determine gastrointestinal site of absorption and systemic exposure of azathioprine.

Authors:  J M Gervasio; R O Brown; J Lima; M G Tabbaa; T Abell; R Werkman; L J Haberer; L J Hak
Journal:  Dig Dis Sci       Date:  2000-08       Impact factor: 3.199

4.  Assay of thioinosinic acid, an active metabolite of azathioprine, in human lymphocytes.

Authors:  L Fletcher; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1980-09       Impact factor: 4.335

Review 5.  Comparative tolerability of therapies for ulcerative colitis.

Authors:  Sandro Ardizzone; Gabriele Bianchi Porro
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

6.  Combination treatment with 6-mercaptopurine and allopurinol in HepG2 and HEK293 cells - Effects on gene expression levels and thiopurine metabolism.

Authors:  Sofie Haglund; Svante Vikingsson; Sven Almer; Jan Söderman
Journal:  PLoS One       Date:  2017-03-09       Impact factor: 3.240

Review 7.  Pharmacology and Optimization of Thiopurines and Methotrexate in Inflammatory Bowel Disease.

Authors:  Mehmet Coskun; Casper Steenholdt; Nanne K de Boer; Ole Haagen Nielsen
Journal:  Clin Pharmacokinet       Date:  2016-03       Impact factor: 5.577

  7 in total

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