Literature DB >> 4758830

Bactericidal effect of combinations of nalidixic acid and various antibiotics on Enterobacteriaceae.

J Michel, R Luboshitzky, T Sacks.   

Abstract

The activity of nalidixic acid combined with each of 10 other antimicrobial agents on 95 strains of Enterobacteriaceae was studied. Synergism was found less often than antagonism, and the commonest outcome was indifference. Combinations of nalidixic acid with kanamycin, gentamicin, or colistin were more often synergistic than antagonistic, whereas with the other antibiotics the combination was more often antagonistic than synergistic. Synergistic effects were more common with Shigella than with other genera. In vitro examination for synergism or antagonism appears to be advisable before nalidixic acid is used therapeutically in combination with other antimicrobial agents.

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Year:  1973        PMID： 4758830      PMCID： PMC444529          DOI： 10.1128/AAC.4.3.201

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

1.  [Rifampicin: a bacteriostatic and bactericidal agent].

Authors:  J G Baudens; Y A Chabbert
Journal:  Pathol Biol (Paris)       Date:  1969-04

2.  [Study of nalidixic acid activity on 3186 strains of Gram negative bacilli. Application to the treatment of urinary infections].

Authors:  R Chamfeuil; H Curcier
Journal:  Presse Med       Date:  1969-11-15       Impact factor: 1.228

3.  The interaction patterns of combined antibacterial agents. Experiments with two agardiffusion methods.

Authors:  R P Mouton; A Koelman
Journal:  Chemotherapy       Date:  1966       Impact factor: 2.544

4.  Nalidixic acid and oxolinic acid in the treatment of chronic bacteriuria.

Authors:  E Atlas; H Clark; F Silverblatt; M Turck
Journal:  Ann Intern Med       Date:  1969-04       Impact factor: 25.391

5.  [Inhibitory action of nitrofurantoin on the bacteriostatic power in vitro of nalidixic acid].

Authors:  J D Piguet
Journal:  Ann Inst Pasteur (Paris)       Date:  1969-01

6.  [Interaction between nalidixic acid and some antibacterial substances].

Authors:  A Dominici; C Perini
Journal:  Antibiotica       Date:  1967-09

7.  [Antibacterial activity in vitro of nalidixic acid-neomycin].

Authors:  R Auriti; L Ravagnan
Journal:  Antibiotica       Date:  1968-06

8.  Antibiotic susceptibility of pathogenic microorganisms isolated in 1969.

Authors:  S S Schneierson
Journal:  N Y State J Med       Date:  1970-07-15

9.  Nalidixic acid: clinical and laboratory studies.

Authors:  S M Finegold; L G Miller; D Posnick; D K Patterson; A Davis
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1966

10.  A critical evaluation of nalidixic acid in urinary-tract infections.

Authors:  A R Ronald; M Turck; R G Petersdorf
Journal:  N Engl J Med       Date:  1966-11-17       Impact factor: 91.245
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  8 in total

Review 1.  Principles of combination therapy.

Authors:  S Levin; A A Harris
Journal:  Bull N Y Acad Med       Date:  1975-10

2.  Effect of leukocyte hydrolases on bacteria. XV. Inhibition by antibiotics, metabolic inhibitors, and ultraviolet irradiation of the release by leukocyte extracts, trypsin, and lysozyme of lipopolysaccharide from gram-negative bacteria.

Authors:  D Cohen; J Michel; M Ferne; S Bergner-Rabinowitz; I Ginsburg
Journal:  Inflammation       Date:  1979-09       Impact factor: 4.092

3.  Bactericidal effect of combinations of antimicrobial drugs and antineoplastic antibiotics against Staphylococcus aureus.

Authors:  J Y Jacobs; J Michel; T Sacks
Journal:  Antimicrob Agents Chemother       Date:  1979-04       Impact factor: 5.191

4.  Antimicrobial susceptibilities of shigellae isolated in Houston, Texas, in 1974.

Authors:  P A Byers; H L Dupont; M C Goldschmidt
Journal:  Antimicrob Agents Chemother       Date:  1976-02       Impact factor: 5.191

5.  Mechanis of chlorampenicol-cephalordine synergism on Enerobacteiaeae.

Authors:  J Michel; H Bornstein; R Luboshitzky; T Sacks
Journal:  Antimicrob Agents Chemother       Date:  1975-06       Impact factor: 5.191

6.  Trimethoprim enhances the antibacterial activity of nalidixic and oxolinic acids and delays the emergence of resistance.

Authors:  A Bertolini; M Castelli; S Genedani; M Garuti
Journal:  Experientia       Date:  1980-02-15

7.  Microdilution transfer plate technique for determining in vitro synergy of antimicrobial agents.

Authors:  P F Dougherty; D W Yotter; T R Matthews
Journal:  Antimicrob Agents Chemother       Date:  1977-02       Impact factor: 5.191

8.  Antibacterial activity of methyl gallate isolated from Galla Rhois or carvacrol combined with nalidixic acid against nalidixic acid resistant bacteria.

Authors:  Jang-Gi Choi; Ok-Hwa Kang; Young-Seob Lee; You-Chang Oh; Hee-Sung Chae; Hye-Jin Jang; Dong-Won Shin; Dong-Yeul Kwon
Journal:  Molecules       Date:  2009-05-11       Impact factor: 4.411
  8 in total

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