Literature DB >> 475592

The effects of aspirin on the development of the mouse third molar. A potential screening system for weak teratogens.

C L Berry, C D Nickols.   

Abstract

Aspirin is teratogenic at high doses in rodents. A dose related effect is shown at much lower levels in an animal testing system which permits subthreshold effects on development to be measured. This system, which depends on changes in tooth size in the mouse, has advantages in assessing weak or cumulative teratogens.

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Year:  1979        PMID: 475592     DOI: 10.1007/bf00353710

Source DB:  PubMed          Journal:  Arch Toxicol        ISSN: 0340-5761            Impact factor:   5.153


  15 in total

1.  ASPIRIN-INDUCED CLEFT LIP AND OTHER MALFORMATIONS IN MICE.

Authors:  D G TRASLER
Journal:  Lancet       Date:  1965-03-13       Impact factor: 79.321

2.  Rapid determination of salicylate in biological fluids.

Authors:  P TRINDER
Journal:  Biochem J       Date:  1954-06       Impact factor: 3.857

3.  Aetiological factors in childhood neoplasia.

Authors:  C L Berry
Journal:  J Clin Pathol       Date:  1976-11       Impact factor: 3.411

4.  Prenatal exposure to oral contraceptives and transposition of the great vessels in man.

Authors:  M Yasuda; J R Miller
Journal:  Teratology       Date:  1975-12

5.  Contraceptive hormones and congenital heart disease.

Authors:  J J Nora; A H Nora
Journal:  Teratology       Date:  1977-06

6.  Absence of the third molar tooth in the mouse: its relevance to human malformation.

Authors:  C L Berry; J Germain
Journal:  J Pathol       Date:  1972-09       Impact factor: 7.996

7.  Studies on metabolism and identification of the causative agent in aspirin teratogenesis in rats.

Authors:  C A Kimmel; J G Wilson; H J Schumacher
Journal:  Teratology       Date:  1971-02

8.  Familial predisposition in man.

Authors:  J H Edwards
Journal:  Br Med Bull       Date:  1969-01       Impact factor: 4.291

9.  Normal and experimental variations in proportions of skeleton of chick embryo wing.

Authors:  D Summerbell
Journal:  Nature       Date:  1978-08-03       Impact factor: 49.962

10.  Potentiation of methotrexate embryolethality by aspirin in rats.

Authors:  D C Woo; R M McClain; R M Hoar
Journal:  Teratology       Date:  1978-02
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  1 in total

1.  Dexamethasone inhibits BMP7-induced osteogenic differentiation in rat dental follicle cells via the PI3K/AKT/GSK-3β/β-catenin pathway.

Authors:  Jing Tang; Mao-Feng Qing; Min Li; Zhi Gao
Journal:  Int J Med Sci       Date:  2020-09-21       Impact factor: 3.738

  1 in total

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