Literature DB >> 4749282

The apparent stimulation of proteolysis by adenosine triphosphate in tissue homogenates.

D F Goldspink, A L Goldberg.   

Abstract

Reports that ATP promotes proteolysis in tissue homogenates were reinvestigated. Although ATP increased production of material reacting with ninhydrin or Folin-phenol reagent, ATP did not stimulate protein degradation in such extracts. AMP and adenosine acted similarly to ATP. Deamination of the added nucleotides to produce ammonia caused the increase in ninhydrin-positive material.

Entities:  

Mesh：

Substances：

Year:  1973        PMID： 4749282      PMCID： PMC1177883          DOI： 10.1042/bj1340829

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  16 in total

1.  Effects of protease inhibitors on protein breakdown in Escherichia coli.

Authors:  W F Prouty; A L Goldberg
Journal:  J Biol Chem       Date:  1972-05-25       Impact factor: 5.157

2.  Activating effect of adenosine-5'-triphosphate on the neutral proteolytic activity of liver homogenates.

Authors:  C R Umaña
Journal:  Proc Soc Exp Biol Med       Date:  1970-12

3.  The purine nucleotide cycle. The production of ammonia from aspartate by extracts of rat skeletal muscle.

Authors:  K Tornheim; J M Lowenstein
Journal:  J Biol Chem       Date:  1972-01-10       Impact factor: 5.157

4.  ATP activation of the neutral proteolytic activity. A widespread phenomenon.

Authors:  C R Umaña; G Feldman
Journal:  Proc Soc Exp Biol Med       Date:  1971-10

5.  The rapid separation of nucleotides in cell extracts using high-pressure liquid chromatography.

Authors:  P R Brown
Journal:  J Chromatogr       Date:  1970-10-21

6.  Protein catabolism in rat liver homogenates. A re-evaluation of the energy requirement for protein catabolism.

Authors:  C O Brostrom; H Jeffay
Journal:  J Biol Chem       Date:  1970-08-25       Impact factor: 5.157

7.  Studies on the degradation of tyrosine aminotransferase in hepatoma cells in culture. Influence of the composition of the medium and adenosine triphosphate dependence.

Authors:  A Hershko; G M Tomkins
Journal:  J Biol Chem       Date:  1971-02-10       Impact factor: 5.157

8.  Reassessment of alkaline proteases and the presence of xanthine oxidase in mouse muscle.

Authors:  J Willemot; M Lalanne; L Berlinguet
Journal:  Arch Biochem Biophys       Date:  1969-09       Impact factor: 4.013

9.  Protein degradation at neutral pH. Possible enzymic and control mechanisms.

Authors:  C R Umaña
Journal:  Proc Soc Exp Biol Med       Date:  1971-10

10.  Degradation of abnormal proteins in Escherichia coli (protein breakdown-protein structure-mistranslation-amino acid analogs-puromycin).

Authors:  A L Goldberg
Journal:  Proc Natl Acad Sci U S A       Date:  1972-02       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.