Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Strategy in drug design. Cluster analysis as an aid in the selection of substituents.

Literature DB >> 4747964

Strategy in drug design. Cluster analysis as an aid in the selection of substituents.

C Hansch, S H Unger, A B Forsythe.

Abstract

Entities: Gene

Mesh：

Year: 1973 PMID： 4747964 DOI： 10.1021/jm00269a004

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

Keyword Cloud
Cited

× No keyword cloud information.

10 in total

1. Binding of novel fullerene inhibitors to HIV-1 protease: insight through molecular dynamics and molecular mechanics Poisson-Boltzmann surface area calculations.

Authors: Haralambos Tzoupis; Georgios Leonis; Serdar Durdagi; Varnavas Mouchlis; Thomas Mavromoustakos; Manthos G Papadopoulos
Journal: J Comput Aided Mol Des Date: 2011-10-04 Impact factor: 3.686

2. Quantitative Series Enrichment Analysis (QSEA): a novel procedure for 3D-QSAR analysis.

Authors: Bernd Wendt; Richard D Cramer
Journal: J Comput Aided Mol Des Date: 2008-02-27 Impact factor: 3.686

3. QSAR modeling: where have you been? Where are you going to?

Authors: Artem Cherkasov; Eugene N Muratov; Denis Fourches; Alexandre Varnek; Igor I Baskin; Mark Cronin; John Dearden; Paola Gramatica; Yvonne C Martin; Roberto Todeschini; Viviana Consonni; Victor E Kuz'min; Richard Cramer; Romualdo Benigni; Chihae Yang; James Rathman; Lothar Terfloth; Johann Gasteiger; Ann Richard; Alexander Tropsha
Journal: J Med Chem Date: 2014-01-06 Impact factor: 7.446

Review 10. Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies.

Authors: Katarina Nikolic; Lazaros Mavridis; Teodora Djikic; Jelica Vucicevic; Danica Agbaba; Kemal Yelekci; John B O Mitchell
Journal: Front Neurosci Date: 2016-06-10 Impact factor: 4.677

10 in total

Strategy in drug design. Cluster analysis as an aid in the selection of substituents.

1. Binding of novel fullerene inhibitors to HIV-1 protease: insight through molecular dynamics and molecular mechanics Poisson-Boltzmann surface area calculations.

2. Quantitative Series Enrichment Analysis (QSEA): a novel procedure for 3D-QSAR analysis.

3. QSAR modeling: where have you been? Where are you going to?

4. Pattern recognition study of QSAR substituent descriptors.

5. Distance geometry analysis of ligand binding to drug receptor sites.

6. [Concepts for the synthesis of new biologically active substances].

7. Perspectives in QSAR: computer chemistry and pattern recognition.

8. Probing Protein Surfaces: QSAR Analysis with Helix Mimetics.

9. Parameter and structure-activity data bases: management for maximum utility.

Review 10. Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies.