Literature DB >> 474305

Anti-inflammatory action following liver damage in the rat.

D A Lewis, D P Parrott, J Bird, R Best.   

Abstract

A high molecular weight protein fraction, obtained by column chromatography of saline extracts of the livers of rats that had previously been treated with dimethylnitrosamine, was found to have anti-inflammatory activity against carrageenin induced inflammation in the rat. Evidence was presented that the anti-inflammatory activity may be due to a protein fragment produced by proteolysis of a larger molecule.

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Year:  1979        PMID： 474305     DOI： 10.1007/bf02024735

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  11 in total

1.  Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs.

Authors:  C A WINTER; E A RISLEY; G W NUSS
Journal:  Proc Soc Exp Biol Med       Date:  1962-12

2.  Therapeutic effect of induced jaundice in rheumatoid arthritis.

Authors:  F GARDNER; A STEWART; F O MacCALLUN
Journal:  Br Med J       Date:  1945-11-17

3.  Determination of serum proteins by means of the biuret reaction.

Authors:  A G GORNALL; C J BARDAWILL; M M DAVID
Journal:  J Biol Chem       Date:  1949-02       Impact factor: 5.157

4.  The control of rheumatic disease by endogenous protein.

Authors:  D A Lewis; R B Capstick; R Best
Journal:  Biochem Pharmacol       Date:  1976-06-15       Impact factor: 5.858

5.  Separation of irritancy from the anti-inflammatory component of inflammation exudate.

Authors:  M E Billingham; B V Robinson
Journal:  Br J Pharmacol       Date:  1972-02       Impact factor: 8.739

6.  Effect of hepatic injury on adjuvant arthritis.

Authors:  R S Pinals
Journal:  Ann Rheum Dis       Date:  1973-09       Impact factor: 19.103

7.  New methods for the determination of elastase.

Authors:  H Rinderknecht; M C Geokas; P Silverman; Y Lillard; B J Haverback
Journal:  Clin Chim Acta       Date:  1968-02       Impact factor: 3.786

8.  Role of the liver in inflammation.

Authors:  M E Billingham; A H Gordon; B V Robinson
Journal:  Nat New Biol       Date:  1971-05-05

9.  Determination of alpha-2-macroglobulin as trypsin-protein esterase.

Authors:  P O Ganrot
Journal:  Clin Chim Acta       Date:  1966-10       Impact factor: 3.786

10.  The possible occurrence of endogenous anti-inflammatory substances in the blood of injured rats.

Authors:  D C Atkinson; R Hicks
Journal:  Br J Pharmacol       Date:  1975-01       Impact factor: 8.739
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  2 in total

1.  Putrescine--a potent endogenous anti-inflammatory substance in inflammatory exudates.

Authors:  J Bird; S Mohd-Hidir; D A Lewis
Journal:  Agents Actions       Date:  1983-06

2.  Inflammation, counter irritation and rat serum acute phase alpha 2-macroglobulin levels.

Authors:  B A Baldo
Journal:  Agents Actions       Date:  1982-07
  2 in total

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