Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Inhibition of liver fibrosis by 1-azetidine-2-carboxylic acid in rats treated with carbon tetrachloride.

Literature DB >> 4729042

Inhibition of liver fibrosis by 1-azetidine-2-carboxylic acid in rats treated with carbon tetrachloride.

Abstract

L-Azetidine-2-carboxylic acid (AZC), an analogue of proline, has been shown to partially ameliorate hepatic cirrhosis induced in rats by CCl(4). AZC caused a diminution in formation of collagen in the liver accompanied by a relative decrease in the pool of free proline. The synthesis of noncollagenous proteins in the livers of treated rats did not appear to be affected.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1973 PMID： 4729042 PMCID： PMC302504 DOI： 10.1172/JCI107436

Source DB: PubMed Journal: J Clin Invest ISSN： 0021-9738 Impact factor: 14.808

22 in total

1. A method for the simultaneous measurement of the radioactivity of proline-C14 and hydroxyproline-C14 in biological materials.

Authors: B PETERKOFSKY; D J PROCKOP
Journal: Anal Biochem Date: 1962-11 Impact factor: 3.365

2. Quantitative differences in proline tRNA content of rat liver and granulation tissue.

Authors: K W Lanks; I B Weinstein
Journal: Biochem Biophys Res Commun Date: 1970-08-11 Impact factor: 3.575

3. Analysis of the amino acid binding to the proline transfer ribonucleic acid synthetase of Escherichia coli.

Authors: T S Papas; A H Mehler
Journal: J Biol Chem Date: 1970-04-10 Impact factor: 5.157

4. Biosynthesis of abnormal collagens with amino acid analogues. I. Incorporation of L-azetidine-2-carboxylic acid and cis-4-fluoro-L-proline into protocollagen and collagen.

Authors: T Takeuchi; D J Prockop
Journal: Biochim Biophys Acta Date: 1969-02-04

5. Incorporation of 3,4-dehydroproline into protocollagen and collagen. Limited hydroxylation of proline and lysine in the same polypeptide.

Authors: J Rosenbloom; D J Prockop
Journal: J Biol Chem Date: 1970-07-10 Impact factor: 5.157

6. Collagen biosynthesis in cirrhotic rat liver slices a regulatory mechanism.

Authors: M Rojkind; L Diaz de León
Journal: Biochim Biophys Acta Date: 1970-10-15

7. Collagen biosynthesis in normal and cirrhotic rat liver slices.

Authors: A Huberman; A Recio; M Rojkind
Journal: Proc Soc Exp Biol Med Date: 1969-05

8. Biosynthesis of abnormal collagens with amino acid analogues. II. Inability of cartilage cells to extrude collagen polypeptides containing L-azetidine-2-carboxylic acid or cis-4-fluoro-L-proline.

Authors: T Takeuchi; J Rosenbloom; D J Prockop
Journal: Biochim Biophys Acta Date: 1969-02-04

9. Amino acid transport in bone. Evidence for separate transport systems for neutral amino and imino acids.

Authors: G A Finerman; L E Rosenberg
Journal: J Biol Chem Date: 1966-04-10 Impact factor: 5.157

10. The relationship between the free pool of proline and collagen content in human liver cirrhosis.

Authors: D Kershenobich; F J Fierro; M Rojkind
Journal: J Clin Invest Date: 1970-12 Impact factor: 14.808

6 in total

1. Regional brain GABA metabolism and release during hepatic coma produced in rats chronically treated with carbon tetrachloride.

Authors: M Díaz-Muñoz; R Tapia
Journal: Neurochem Res Date: 1988-01 Impact factor: 3.996

2. Collagen metabolism in the liver. An annotated and supplemented report of a workshop at the National Institutes of Health on February 28 and March 1, 1977.

Authors:
Journal: Am J Dig Dis Date: 1978-07