Literature DB >> 4727057

The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients.

S Kumar, G Taylor.   

Abstract

The uptake of tritiated thymidine by lymphocytes from 100 cancer patients and 31 normal subjects was tested in the presence and absence of phytohaemagglutinin (PHA) in a medium containing autologous or homologous serum. Significant differences were found between normal subjects and cancer patients in both the time course and degree of uptake. Serum from normal individuals restored the response of lymphocytes from cancer patients towards normality whilst serum from other cancer patients had no effect. Serum from cancer patients impaired the response of normal lymphocytes.

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Year:  1973        PMID： 4727057      PMCID： PMC477799          DOI： 10.1136/jcp.26.7.476

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  17 in total

1.  Lymphocyte response to P.H.A. in patients with lung cancer.

Authors:  J Ducos; J Migueres; P Colombies; A Kessous; N Poujoulet
Journal:  Lancet       Date:  1970-05-23       Impact factor: 79.321

2.  Transformation of human lymphocytes: inhibition by homologous alpha globulin.

Authors:  S R Cooperband; H Bondevik; K Schmid; J A Mannick
Journal:  Science       Date:  1968-03-15       Impact factor: 47.728

3.  Effect of plasma from patients with carcinoma on in vitro lymphocyte transformation.

Authors:  M Silk
Journal:  Cancer       Date:  1967-12       Impact factor: 6.860

4.  Reactivity of human lymphocytes to autologous and homologous serum.

Authors:  A B Bredt; M R Mardiney
Journal:  J Immunol       Date:  1969-06       Impact factor: 5.422

5.  Variation in the response of normal lymphocytes to PHA.

Authors:  O R McIntyre; A F Cole
Journal:  Int Arch Allergy Appl Immunol       Date:  1969

6.  Effect of serum from cancer patients on homologous lymphocyte cultures.

Authors:  E K Golob; T Israsena; A C Quatrale; K L Becker
Journal:  Cancer       Date:  1969-02       Impact factor: 6.860

7.  Delayed hypersensitivity in cancer patients: cutaneous and in vitro lymphocyte response to specific antigens.

Authors:  H S Nelson
Journal:  J Natl Cancer Inst       Date:  1969-05       Impact factor: 13.506

8.  Inhibition of transformation of normal lymphocytes by plasma factor from patients with Hodgkin's disease and cancer.

Authors:  P G Scheurlen; W Schneider; A Pappas
Journal:  Lancet       Date:  1971-12-04       Impact factor: 79.321

9.  A plasma factor in chronic lymphocytic leukemia which stimulates DNA synthesis and blastogenesis in leukocyte cultures.

Authors:  S Kasakura; L Lowenstein
Journal:  Blood       Date:  1967-04       Impact factor: 22.113

10.  The response of human leucocyte cultures to stimulation by tuberculin and phytohaemagglutinin measured by the uptake of radioactive thymidine.

Authors:  M Hartog; M J Cline; G M Grodsky
Journal:  Clin Exp Immunol       Date:  1967-03       Impact factor: 4.330
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  6 in total

Review 1.  [The immunology of malignant melanoma (author's transl)].

Authors:  G Schieferstein
Journal:  Klin Wochenschr       Date:  1978-03-15

2.  Reduced lymphocyte transformation in early cancer of the breast.

Authors:  L A Knight; W M Davidson
Journal:  J Clin Pathol       Date:  1975-05       Impact factor: 3.411

3.  Geographic correlation between mortality from primary hepatic carcinoma and prevalence of hepatitis B surface antigen in Greece.

Authors:  D Trichopoulos; G Papaevangelou; M Violaki; C Vissoulis; L Sparros; O N Manousos
Journal:  Br J Cancer       Date:  1976-07       Impact factor: 7.640

4.  Effects of autologous plasma on lymphocyte transformation in malaria and in acute protein-energy malnutrition. Comparison of purified lymphocyte and whole blood cultures.

Authors:  D L Moore; B Heyworth; J Brown
Journal:  Immunology       Date:  1977-12       Impact factor: 7.397

5.  Lymphocyte transformation in cancer patients: variation in results according to technique.

Authors:  G M Gyte; S M Watkins
Journal:  J Clin Pathol       Date:  1978-02       Impact factor: 3.411

6.  Tropical cirrhosis and hepatoma.

Authors:  A Coady
Journal:  J R Coll Physicians Lond       Date:  1976-01
  6 in total

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