Literature DB >> 4724191

The effects of an anti-atherosclerotic drug, pyridinolcarbamate, on heart, vascular and brain biogenic amines.

B A Berkowitz, H Hidaka, S Spector.   

Abstract

The anti-atherosclerotic drug pyridinolcarbamate was investigated in the rat for its effects on heart, blood vessel and brain biogenic amines. The drug increased the concentration of noradrenaline in all tissues and of noradrenaline and 5-hydroxytryptamine in the brain. The possibility of a link between biogenic amines and atherosclerotic disease is discussed.

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Year:  1973        PMID： 4724191      PMCID： PMC1776097          DOI： 10.1111/j.1476-5381.1973.tb08239.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  13 in total

1.  A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines.

Authors:  A H ANTON; D F SAYRE
Journal:  J Pharmacol Exp Ther       Date:  1962-12       Impact factor: 4.030

2.  Preventive effectiveness of MAO inhibitor and ineffectiveness of prothrombinopenic anticoagulant against increase in plasma thrombin activity by adrenaline, cholesterol, and traumatization.

Authors:  T SHIMAMOTO; K TAKEUCHI; T ISHIOKA
Journal:  Am Heart J       Date:  1962-07       Impact factor: 4.749

3.  A rapid spectrophotometric assay of mono-amine oxidase based on the rate of disappearance of kynuramine.

Authors:  H WEISSBACH; T E SMITH; J W DALY; B WITKOP; S UDENFRIEND
Journal:  J Biol Chem       Date:  1960-04       Impact factor: 5.157

4.  Effect of psychotropic drugs on tryptophan concentration in the rat brain.

Authors:  A Tagliamonte; P Tagliamonte; J Perez-Cruet; S Stern; G L Gessa
Journal:  J Pharmacol Exp Ther       Date:  1971-06       Impact factor: 4.030

5.  The effects of pyridinolcarbamate on induced atherosclerosis in cynomolgus monkeys (Macaca ira).

Authors:  M R Malinow; P McLaughlin; A Perley
Journal:  Atherosclerosis       Date:  1972 Jan-Feb       Impact factor: 5.162

6.  Cardiac adrenergic mechanisms in rabbits with experimentally produced coronary atherosclerosis.

Authors:  R A Gillis; K I Melville
Journal:  Atherosclerosis       Date:  1972 Jan-Feb       Impact factor: 5.162

7.  Disposition of histamine in mammalian blood vessels.

Authors:  R D Howland; S Spector
Journal:  J Pharmacol Exp Ther       Date:  1972-08       Impact factor: 4.030

8.  Norepinephrine in blood vessels: concentration, binding, uptake and depletion.

Authors:  B A Berkowitz; J H Tarver; S Spector
Journal:  J Pharmacol Exp Ther       Date:  1971-04       Impact factor: 4.030

9.  Amphetamine toxicity in hyperthyroid mice: effects on endogenous catecholamines.

Authors:  K E Moore
Journal:  Biochem Pharmacol       Date:  1965-12       Impact factor: 5.858

10.  Resistance of noradrenaline in blood vessels to depletion by 6-hydroxydopamine or immunosympathectomy.

Authors:  B A Berkowitz; S Spector; J H Tarver
Journal:  Br J Pharmacol       Date:  1972-01       Impact factor: 8.739
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