Literature DB >> 4723782

The state of phosphorylation in vivo of membrane-bound phosphoproteins in rat brain.

M Weller, R Rodnight.   

Abstract

The alkali-labile P content of membrane protein prepared from rapidly frozen rat brain was measured, CuSO(4) being used to inhibit protein phosphatase activity during subcellular fractionation. The P content of the membrane fraction was significantly increased (+12%) over the control value by incubation of homogenates with ATP before fractionation. This suggests that the membrane protein in rat brain is normally only partially phosphorylated.

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Year:  1973        PMID: 4723782      PMCID: PMC1177709          DOI: 10.1042/bj1330387

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  2 in total

1.  Protein kinase activity in membrane preparations from ox brain. Stimulation of intrinsic activity by adenosine 3':5'-cyclic monophosphate.

Authors:  M Weller; R Rodnight
Journal:  Biochem J       Date:  1973-03       Impact factor: 3.857

2.  Turnover of protein-bound phosphorylserine in membrane preparations from ox brain catalysed by intrinsic kinase and phosphatase activity.

Authors:  M Weller; R Rodnight
Journal:  Biochem J       Date:  1971-09       Impact factor: 3.857

  2 in total
  3 in total

1.  Regulation of 3',5'-cyclic AMP-dependent protein kinase in the plasma membrane of cod (Gadus callarius) and mouse islets.

Authors:  B DPAVIS; N R Lazarus
Journal:  J Membr Biol       Date:  1975       Impact factor: 1.843

2.  Distribution of membrane-bound cyclic AMP-dependent protein kinase in plasma membranes of cells of the kidney cortex.

Authors:  R Kinne; L J Shlatz; E Kinne-Saffran; I L Schwartz
Journal:  J Membr Biol       Date:  1975-11-07       Impact factor: 1.843

3.  Protein kinase activity stimulated by adenosine 3' :5'-cyclic monophosphate in synaptic-membrane fragments from ox brain. Inhibition of intrinsic activity by free and membrane-bound calcium ions.

Authors:  M Weller; R Rodnight
Journal:  Biochem J       Date:  1974-09       Impact factor: 3.857

  3 in total

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