| Literature DB >> 471186 |
S van Noorden, J M Polak, S R Bloom, M G Bryant.
Abstract
Vasoactive intestinal polypeptide (VIP) is a widely distributed neuropeptide which has recently been found in the hypothalamus and in hypothalamo-hypophyseal portal blood. We have examined the pituitary of several mammalian species for the presence of VIP by immunocytochemistry and radioimmunoassay and report here that the pars nervosa contains a considerable quantity of VIP (100-250 fmol/mg) which, in the dog, can be shown to be present in nerve fibres. It is possible that neurohypophyseal VIP may be a local releasing agent for vasopressin.Entities:
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Year: 1979 PMID: 471186 DOI: 10.1111/j.1365-2990.1979.tb00667.x
Source DB: PubMed Journal: Neuropathol Appl Neurobiol ISSN: 0305-1846 Impact factor: 8.090