Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Metoclopramide in gastrooesophageal reflux.

Literature DB >> 4706908

Metoclopramide in gastrooesophageal reflux.

Abstract

In 30 patients with gastrooesophageal reflux, intravenous metoclopramide (Maxolon) has been shown to increase the gastrooesophageal sphincter pressure. The rise is dose-related until a maximum pressure, proportional to the resting sphincter tone, is reached. The effect is reversed by atropine. Peristaltic waves are increased in pressure by metoclopramide.In 18 patients with gastrooesophageal reflux intravenous metoclopramide diminished the frequency of reflux episodes and increased the rate at which the oesophagus emptied itself of an acid load.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1973 PMID： 4706908 PMCID： PMC1412597 DOI： 10.1136/gut.14.4.275

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

7 in total

1. A MULTIPHASE ESOPHAGEAL PH TEST FOR GASTROESOPHAGEAL REFLUX.

Authors: V A PICCONE; J R GUTELIUS; J R MCCORRISTON
Journal: Surgery Date: 1965-05 Impact factor: 3.982

2. Acid clearing from the distal esophagus.

Authors: D J Booth; W T Kemmerer; D B Skinner
Journal: Arch Surg Date: 1968-05

3. Assessment of distal esophageal function in patients with hiatal hernia and-or gastroesophageal reflux.

Authors: D B Skinner; D J Booth
Journal: Ann Surg Date: 1970-10 Impact factor: 12.969

4. [Action of methoclopramide on different portions of isolated rabbit intestine and on the "in situ" intestine].

Authors: D Coullaud; J Lévêque
Journal: Pathol Biol Date: 1966-10

5. The effect of metoclopramide on the gastroesophageal junctional zone and the distal esophagus in man.

Authors: P Heitmann; N Möller
Journal: Scand J Gastroenterol Date: 1970 Impact factor: 2.423

6. Gastrointestinal effects of metoclopramide in man. In vitro experiments with human smooth muscle preparations.

Authors: M Eisner
Journal: Br Med J Date: 1968-12-14

7. Effect of intravenous metoclopramide on gastrooesophageal reflux.

Authors: J N Glanville; W D Walls
Journal: Gut Date: 1972-01 Impact factor: 23.059

7 in total

17 in total

1. Reflux esophagitis.

Authors: W J Dodds; W J Hogan; W N Miller
Journal: Am J Dig Dis Date: 1976-01

Review 2. Some aspects of medical management of gastrointestinal disease. I.

Authors: B W Badley
Journal: Can Med Assoc J Date: 1975-01-25 Impact factor: 8.262

3. Diagnosing hiatus hernia.

Authors: G E Sinclair
Journal: Can Fam Physician Date: 1978-10 Impact factor: 3.275

4. A double-blind dose ranging study of BRL 24924 and metoclopramide on lower oesophageal sphincter pressure in healthy volunteers.

Authors: C S Robertson; S J Ledingham; S M Cooper; D F Evans
Journal: Br J Clin Pharmacol Date: 1989-09 Impact factor: 4.335

Metoclopramide in gastrooesophageal reflux.

1. A MULTIPHASE ESOPHAGEAL PH TEST FOR GASTROESOPHAGEAL REFLUX.

2. Acid clearing from the distal esophagus.

3. Assessment of distal esophageal function in patients with hiatal hernia and-or gastroesophageal reflux.

4. [Action of methoclopramide on different portions of isolated rabbit intestine and on the "in situ" intestine].

5. The effect of metoclopramide on the gastroesophageal junctional zone and the distal esophagus in man.

6. Gastrointestinal effects of metoclopramide in man. In vitro experiments with human smooth muscle preparations.

7. Effect of intravenous metoclopramide on gastrooesophageal reflux.

1. Reflux esophagitis.

Review 2. Some aspects of medical management of gastrointestinal disease. I.

3. Diagnosing hiatus hernia.

4. A double-blind dose ranging study of BRL 24924 and metoclopramide on lower oesophageal sphincter pressure in healthy volunteers.

5. [Applications of endoscopy, manometry, and conservative therapy (author's transl)].

6. Amyloidosis mimics achalasia's effect on lower esophageal sphincter.

7. Oesophageal acid clearing: one factor in the production of reflux oesophagitis.

8. L-Dopa inhibits metoclopramide stimulation of the lower esophageal sphincter in man.

Review 9. Metoclopramide: a review of its pharmacological properties and clinical use.

10. Metoclopramide inhibits development of esophageal varices in rat model.