Literature DB >> 4705984

Demonstration of the acyl-enzyme mechanism for the hydrolysis of peptides and anilides by chymotrypsin.

J Fastrez, A R Fersht.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1973        PMID： 4705984     DOI： 10.1021/bi00735a001

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


× No keyword cloud information.
  14 in total

Review 1.  Substrate-assisted catalysis: molecular basis and biological significance.

Authors:  W Dall'Acqua; P Carter
Journal:  Protein Sci       Date:  2000-01       Impact factor: 6.725

2.  Enzyme specificity under dynamic control II: Principal component analysis of alpha-lytic protease using global and local solvent boundary conditions.

Authors:  N Ota; D A Agard
Journal:  Protein Sci       Date:  2001-07       Impact factor: 6.725

3.  Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor.

Authors:  Elena Zakharova; Martin P Horvath; David P Goldenberg
Journal:  J Mol Biol       Date:  2008-07-30       Impact factor: 5.469

4.  Purification and characterization of halo-alkali-thermophilic protease from Halobacterium sp. strain HP25 isolated from raw salt, Lake Qarun, Fayoum, Egypt.

Authors:  Khaled Elbanna; Ibrahim M Ibrahim; Anne-Marie Revol-Junelles
Journal:  Extremophiles       Date:  2015-05-16       Impact factor: 2.395

5.  alpha-Chymotrypsin as the catalyst for peptide synthesis.

Authors:  K Morihara; T Oka
Journal:  Biochem J       Date:  1977-06-01       Impact factor: 3.857

6.  Enzyme kinetics based on free-energy profiles.

Authors:  S Yagisawa
Journal:  Biochem J       Date:  1995-05-15       Impact factor: 3.857

7.  Proteolytic enzymes in peptide synthesis.

Authors:  D Konopińska; F Muzalewski
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

8.  13C high-resolution nuclear magnetic resonance studies of enzyme-substrate reactions at equilibrium. Substrate studies of chymotrypsin-N-acetyltyrosine semicarbazide complexes.

Authors:  G Robillard; E Shaw; R G Shulman
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

9.  gamma-Glutamyltranspeptidase-catalysed acyl-transfer to the added acceptor does not proceed via the ping-pong mechanism.

Authors:  R C Bateman
Journal:  Biochem J       Date:  1994-12-15       Impact factor: 3.857

10.  Evidence that the lack of high catalytic activity of thiolsubtilisin towards specific substrates may be due to an inappropriately located proton-distribution system. Demonstration of highly nucleophilic character of the thiol group of thiolsubtilisin in the catalytically relevant ionization state of the active centre by use of a two-protonic-state reactivity probe.

Authors:  K Brocklehurst; J P Malthouse
Journal:  Biochem J       Date:  1981-03-01       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.