Literature DB >> 4704093

Treatment of streptococcal pharyngitis. I. Clinical evaluation.

M Rabinovitch, R MacKenzie, M Brazeau, M I Marks.   

Abstract

A study was undertaken to evaluate the therapy of streptococcal pharyngitis. The compliance of 118 patients with beta-hemolytic streptococcal pharyngitis to follow-up was 72%. Of 74 patients checked by means of urine tests 66 took their oral medication. No differences were detected in the clinical and bacteriological results (>98% streptococcal eradication) after the 7th or 10th day of therapy after taking either cephalexin or penicillin.IT WAS CONCLUDED THAT: (a) for effective surveillance and follow-up special attention should be given to the uncooperative segment of the patient population; (b) a seven-day course of penicillin may be satisfactory in the eradication of BHS from the throat; and (c) cephalexin appears to be an effective alternative to penicillin for the treatment of streptococcal pharyngitis.

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Year:  1973        PMID: 4704093      PMCID: PMC1941446     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  11 in total

1.  The effect of penicillin prophylaxis on streptococcal disease rates and the carrier state.

Authors:  L W WANNAMAKER; F W DENNY; W D PERRY; C H RAMMELKAMP; G C ECKHARDT; H B HOUSER; E O HAHN
Journal:  N Engl J Med       Date:  1953-07-02       Impact factor: 91.245

2.  Prophylaxis of acute rheumatic fever by treatment of the preceding streptococcal infection with various amounts of depot penicillin.

Authors:  L W WANNAMAKER; C H RAMMELKAMP; F W DENNY; W R BRINK; H B HOUSER; E O HAHN; J H DINGLE
Journal:  Am J Med       Date:  1951-06       Impact factor: 4.965

3.  Cephalexin: treatment of streptococcal pharyngitis.

Authors:  P H Azimi; H G Cramblett; A J Del rosario; H Kronfol; R E Haynes; M D Hilty
Journal:  J Pediatr       Date:  1972-06       Impact factor: 4.406

4.  Streptococcal tonsillitis in general practice. A comparison of cephalexin and penicillin therapy.

Authors:  D W Gau; R F Horn; R M Solomon; P Johnson; D A Leigh
Journal:  Practitioner       Date:  1972-02

5.  Comparison of efficacy of phenoxymethyl penicillin and buffered penicillin G in treatment of streptococcal pharyngitis.

Authors:  E W Edmond; H G Cramblett; C M Siewers; J Crews; B Ellis; G R Jenkins
Journal:  J Pediatr       Date:  1966-03       Impact factor: 4.406

6.  A mail-in technique for detecting penicillin in urine: application to the study of maintenance of prophylaxis in rheumatic fever patients.

Authors:  M Markowitz; L Gordis
Journal:  Pediatrics       Date:  1968-01       Impact factor: 7.124

7.  Studies in the epidemiology and preventability of rheumatic fever. IV. A quantitative determination of compliance in children on oral penicillin prophylaxis.

Authors:  L Gordis; M Markowitz; A M Lilienfeld
Journal:  Pediatrics       Date:  1969-02       Impact factor: 7.124

8.  Streptococcal pharyngitis therapy: comparison of cyclacillin, cephalexin, and potassium penicillin V.

Authors:  M Stillerman; H D Isenberg
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1970

9.  Cephalexin, a new orally absorbed cephalosporin antibiotic.

Authors:  W E Wick
Journal:  Appl Microbiol       Date:  1967-07

10.  Studies in the home treatment of streptococcal disease. II. A comparison of the efficacy of oral administration of penicillin and intramuscular injection of benzathine penicillin in the treatment of streptococcal pharyngitis.

Authors:  D N MOHLER; D G WALLIN; E G DREYFUS; H J BAKST
Journal:  N Engl J Med       Date:  1956-01-12       Impact factor: 91.245

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  5 in total

1.  Treating Sore Throats: Practice vs. Theory.

Authors:  P Hutten-Czapski
Journal:  Can Fam Physician       Date:  1987-07       Impact factor: 3.275

2.  Randomized, single-blind evaluation of cefadroxil and phenoxymethyl penicillin in the treatment of streptococcal pharyngitis.

Authors:  M E Pichichero; F A Disney; G H Aronovitz; W B Talpey; J L Green; A B Francis
Journal:  Antimicrob Agents Chemother       Date:  1987-06       Impact factor: 5.191

Review 3.  Comparison of European and U.S. results for cephalosporin versus penicillin treatment of group A streptococcal tonsillopharyngitis.

Authors:  M Pichichero; J Casey
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2006-06       Impact factor: 3.267

4.  Treatment of Streptococcal Pharyngitis. II. In vitro studies of antibacterial activity.

Authors:  M I Marks; M Rabinovitch; R MacKenzie; M Brazeau
Journal:  Can Med Assoc J       Date:  1973-05-19       Impact factor: 8.262

5.  Susceptibility of group A beta-hemolytic Streptococcus isolates to penicillin and erythromycin.

Authors:  G R Istre; D F Welch; M I Marks; N Moyer
Journal:  Antimicrob Agents Chemother       Date:  1981-08       Impact factor: 5.191

  5 in total

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