Literature DB >> 4703116

Metabolism of iphosphamide (2-(2-chloroethylamino)-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide) and production of a toxic iphosphamide metabolite.

D L Hill, W R Laster, M C Kirk, S el-Dareer, R F Struck.   

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Year:  1973        PMID: 4703116

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


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  9 in total

1.  Ifosfamide plasma clearance in relation to polymorphic debrisoquine oxidation.

Authors:  P A Philip; L D Lewis; C A James; H J Rogers
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

2.  Mutagenic activity of cyclophosphamide, ifosfamide, and trofosfamide in different genes of escherichia coli and salmonella typhimurium after biotransformation through extracts of rodent liver.

Authors:  J Ellenberger; G Mohn
Journal:  Arch Toxicol       Date:  1975       Impact factor: 5.153

3.  Fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism.

Authors:  L D Lewis; D L Fitzgerald; P G Harper; H J Rogers
Journal:  Br J Clin Pharmacol       Date:  1990-11       Impact factor: 4.335

4.  Preclinical pharmacokinetics and stability of isophosphoramide mustard.

Authors:  J J Zheng; K K Chan; F Muggia
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

5.  Urinary excretion of the enantiomers of ifosfamide and its inactive metabolites in children.

Authors:  J Boos; U Welslau; J Ritter; G Blaschke; G Schellong
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

Review 6.  Comparative activity of ifosfamide and cyclophosphamide.

Authors:  W Brade; S Seeber; K Herdrich
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

7.  Oxazaphosphorine bioactivation and detoxification The role of xenobiotic receptors.

Authors:  Duan Wang; Hongbing Wang
Journal:  Acta Pharm Sin B       Date:  2012-04-01       Impact factor: 11.413

Review 8.  Ifosfamide clinical pharmacokinetics.

Authors:  T Wagner
Journal:  Clin Pharmacokinet       Date:  1994-06       Impact factor: 6.447

9.  Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide.

Authors:  R F Struck; D J Dykes; T H Corbett; W J Suling; M W Trader
Journal:  Br J Cancer       Date:  1983-01       Impact factor: 7.640

  9 in total

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