Literature DB >> 4696466

Evidence for an aldehyde possessing alkylating activity as the primary metabolite of cyclophosphamide.

N E Sladek.   

Abstract

Entities:  

Mesh:

Substances:

Year:  1973        PMID: 4696466

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


× No keyword cloud information.
  12 in total

1.  Proton magnetic resonance studies of the decomposition of 4-hydroxycyclophosphamide, a microsomal metabolite of cyclophosphamide.

Authors:  E J Valente; K K Chan; K L Servis
Journal:  Pharm Res       Date:  1984-03       Impact factor: 4.200

2.  Comparative metabolism of cyclophosphamide and ifosfamide in the mouse using UPLC-ESI-QTOFMS-based metabolomics.

Authors:  Fei Li; Andrew D Patterson; Constance C Höfer; Kristopher W Krausz; Frank J Gonzalez; Jeffrey R Idle
Journal:  Biochem Pharmacol       Date:  2010-06-10       Impact factor: 5.858

3.  Effect of cyclophosphamide on a local graft-versus-host reaction in the rat: influence of sex, disease and different dosage regimens.

Authors:  M W Whitehouse; L Levy; F J Beck
Journal:  Agents Actions       Date:  1973-06

4.  Lymphocyte deactivation by (potential immunosuppressant) alkylating metabolites of cyclophosphamide.

Authors:  M W Whitehouse; F W Beck; M M Dröge; R F Struck
Journal:  Agents Actions       Date:  1974-04

5.  [The evaluation of the cyclophosphamide sensitivity of human tumours by determining the incorporation of tritiated uridine and thymidine into the nucleic acids of human tumor cells in vitro in presence of 4-hydroxycyclophosphamide (author's transl)].

Authors:  G Bastert; H Schmidt-Matthiesen; G Voelcker; G Peter; H J Hohorst
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1975-09-22

6.  Effect of renal insufficiency on the pharmacokinetics of cyclophosphamide and some of its metabolites.

Authors:  F D Juma; H J Rogers; J R Trounce
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

7.  Preclinical pharmacokinetics and stability of isophosphoramide mustard.

Authors:  J J Zheng; K K Chan; F Muggia
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

Review 8.  Methods for analysis of the mutagenicity of indirect mutagens/carcinogens in eukaryotic cells.

Authors:  S Madle; G Obe
Journal:  Hum Genet       Date:  1980       Impact factor: 4.132

9.  Excretion patterns of alkylating metabolites in urine following cyclophosphamide treatment of tumor patients: influence of application route, dosage, liver and kidney function.

Authors:  G Saul; M Matthias; H Rose; I Pradel
Journal:  J Cancer Res Clin Oncol       Date:  1979-07-27       Impact factor: 4.553

10.  Metabolism of high doses of cyclophosphamide.

Authors:  R A Milsted; M Jarman
Journal:  Cancer Chemother Pharmacol       Date:  1982       Impact factor: 3.333

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.