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Literature DB >> 4693151

Glucocorticoid suppression of macrophage migration inhibitory factor.

Abstract

The ability of hydrocortisone to modify antigen-mediated inhibition of macrophage migration, an in vitro correlate of cellular immunity in the guinea pig, was investigated. Only the glucocorticoids, hydrocortisone and dexamethasone, significantly blocked migration inhibitory factor (MIF) activity in pharmacologic concentrations. Hydrocortisone had no effect on antigen "processing" by macrophages, nor on the ability of antigen-stimulated peritoneal exudate lymphocytes to produce MIF. Rather, hydrocortisone antagonized directly the inhibitory effect of MIF on the macrophage.

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Year: 1973 PMID： 4693151 PMCID： PMC2139222 DOI： 10.1084/jem.137.4.1031

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

32 in total

Review 1. The biological activities of soluble lymphocyte products.

Authors: E Pick; J L Turk
Journal: Clin Exp Immunol Date: 1972-01 Impact factor: 4.330

Review 2. Immunosuppressive drugs.

Authors: T Makinodan; G W Santos; R P Quinn
Journal: Pharmacol Rev Date: 1970-06 Impact factor: 25.468

3. Protease activity as a possible mechanism of migration inhibitory factor.

Authors: K Havemann; M Horvat; C P Sodomann; S Bürger
Journal: Eur J Immunol Date: 1972-02 Impact factor: 5.532

4. Demonstration of specific induction of erythrocytes phagocytosis by macrophates from normal, non-sensitized rabbits by a factor released from lymph node cells of immunized rabbits.

Authors: K Barnet; J Pekárek; J Johanovský
Journal: Experientia Date: 1968-09-15

5. McFarland W,+MACFARLAND W: Interaction of lymphocytes and a radioresistant cell in PPD-stimulated human leukocyte cultures.

Authors: G P Schechter
Journal: J Immunol Date: 1970-09 Impact factor: 5.422

6. Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. I. Stimulation by phytohaemagglutinin.

Authors: D Roos; J A Loos
Journal: Biochim Biophys Acta Date: 1970-12-29

7. Inhibition of capillary migration by antigen-antibody complexes.

Authors: L Spitler; H Huber; H H Fudenberg
Journal: J Immunol Date: 1969-02 Impact factor: 5.422

Review 8. In vitro approaches to the mechanism of cell-mediated immune reactions.

Authors: B R Bloom
Journal: Adv Immunol Date: 1971 Impact factor: 3.543

9. The peritoneal exudate lymphocyte. I. Differences in antigen responsiveness between peritoneal exudate and lymph node lymphocytes from immunized guinea pigs.

Authors: D L Rosenstreich; J T Blake; A S Rosenthal
Journal: J Exp Med Date: 1971-11-01 Impact factor: 14.307

10. Mechanism of action of migration inhibitory factor (MIF). I. Evidence for a receptor for MIF present on the peritoneal macrophage but not on the alveolar macrophage.

Authors: R W Leu; A L Eddleston; J W Hadden; R A Good
Journal: J Exp Med Date: 1972-09-01 Impact factor: 14.307

51 in total

1. Effect of prednisolone on the leukocyte counts of ponies and on the reactivity of lymphocytes in vitro and in vivo.

Authors: S P Targowski
Journal: Infect Immun Date: 1975-02 Impact factor: 3.441

2. Corticosteroid can alter antigen expression on alveolar macrophages.

Authors: L Marianayagam; L W Poulter
Journal: Clin Exp Immunol Date: 1991-09 Impact factor: 4.330

3. The effect of various stresses, corticosteroids and adrenergic agents on phagocytosis in the rainbow trout Oncorhynchus mykiss.

Authors: Y K Narnaware; B I Baker; M G Tomlinson
Journal: Fish Physiol Biochem Date: 1994-05 Impact factor: 2.794

Review 4. The macrophage as a secretory cell in chronic inflammation.

Authors: P Davies; A C Allison
Journal: Agents Actions Date: 1976-02

5. Glucocorticoids administered in vivo inhibit human suppressor T lymphocyte function and diminish B lymphocyte responsiveness in in vitro immunoglobulin synthesis.

Authors: A Saxon; R H Stevens; S J Ramer; P J Clements; D T Yu
Journal: J Clin Invest Date: 1978-04 Impact factor: 14.808

6. Human macrophage activation. Modulation of mannosyl, fucosyl receptor activity in vitro by lymphokines, gamma and alpha interferons, and dexamethasone.

Authors: T Mokoena; S Gordon
Journal: J Clin Invest Date: 1985-02 Impact factor: 14.808

7. Arterial steroid injection therapy can inhibit the progression of severe acute hepatic failure toward fulminant liver failure.

Authors: Kazuhiro Kotoh; Munechika Enjoji; Makoto Nakamuta; Tsuyoshi Yoshimoto; Motoyuki Kohjima; Shusuke Morizono; Shinsaku Yamashita; Yuki Horikawa; Kengo Yoshimitsu; Tsuyoshi Tajima; Yoshiki Asayama; Kousei Ishigami; Masakazu Hirakawa
Journal: World J Gastroenterol Date: 2006-11-07 Impact factor: 5.742