Literature DB >> 469016

Electron microscopy of hepatitis B virus components in chronic active liver disease.

R De Vos, M B Ray, V J Desmet.   

Abstract

Eighteen liver biopsy specimens from patients with hepatitis B surface antigen (HBsAg) positive chronic aggressive hepatitis were studied by electron microscopy. All cases were selected on the basis of positive liver cell membrane fluorescence for HBsAg on immunohistochemical investigation. Striking changes in the morphology of the liver cell membrane were observed in nearly all cases. Furthermore, a dual aspect of hepatitis B core antigen (HBcAg) is described. HBcAg particles may occur as either 'naked' or 'cloudy' particles surrounded by semi electron dense material. The nature of the 'cloud' remains to be identified.

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Year:  1979        PMID： 469016      PMCID： PMC1145744          DOI： 10.1136/jcp.32.6.590

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  29 in total

1.  Phalloidin-induced hyperplasia of actin filaments in rat hepatocytes.

Authors:  G Gabbiani; R Montesano; B Tuchweber; M Salas; L Orci
Journal:  Lab Invest       Date:  1975-11       Impact factor: 5.662

2.  Localisation of e-antigen in nuclei of hepatocytes in HBsAg-positive liver diseases.

Authors:  W Arnold; J O Nielsen; F Hardt; K H Meyer zum Büschenfelde
Journal:  Gut       Date:  1977-12       Impact factor: 23.059

3.  Hepatitis B core and surface antigens in liver tissue. Light and electron microscopic localization by the peroxidase-labeled antibody method.

Authors:  G Yamada; P K Nakane
Journal:  Lab Invest       Date:  1977-06       Impact factor: 5.662

4.  Nuclear fluorescence of liver cells for IgG in viral hepatitis B: significance and relation to hepatitis B-core and anti-hepatitis B-core formation.

Authors:  F Gudat; L Bianchi; M Finch; G Krey; Y Endo
Journal:  Klin Wochenschr       Date:  1977-04-01

5.  Immune complexes in hepatocytic nuclei of HB ag-positive chronic hepatitis.

Authors:  M A Gerber; E Sarno; S J Vernace
Journal:  N Engl J Med       Date:  1976-04-22       Impact factor: 91.245

6.  A new antigen-antibody system. Clinical significance in long-term carriers of hepatitis B surface antigen.

Authors:  L O Magnius; A Lindholm; P Lundin; S Iwarson
Journal:  JAMA       Date:  1975-01-27       Impact factor: 56.272

7.  Incidence and clinical significance of e antigen and antibody in acute and chronic liver disease.

Authors:  N Eleftheriou; H C Thomas; J Heathcote; S Sherlock
Journal:  Lancet       Date:  1975-12-13       Impact factor: 79.321

8.  Letter: Detection of e antigen by immunofluorescence in cytoplasm of hepatocytes of HBsAg carriers.

Authors:  C Trepo; L Vitvitski; R Neurath; N Hashimoto; R Schaefer; G Nemoz
Journal:  Lancet       Date:  1976-02-28       Impact factor: 79.321

9.  Distribution patterns of hepatitis B surface antigen (HBsAg) in the liver of hepatitis patients.

Authors:  M B Ray; V J Desmet; J Fevery; J De Groote; A F Bradburne; J Desmyter
Journal:  J Clin Pathol       Date:  1976-02       Impact factor: 3.411

10.  Differential distribution of hepatitis B surface antigen and hepatitis B core antigen in the liver of hepatitis B patients.

Authors:  M B Ray; V J Desmet; A F Bradburne; J Desmyter; J Fevery; J De Groote
Journal:  Gastroenterology       Date:  1976-09       Impact factor: 22.682
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  1 in total

1.  Extracellular Hepatitis B Virus RNAs Are Heterogeneous in Length and Circulate as Capsid-Antibody Complexes in Addition to Virions in Chronic Hepatitis B Patients.

Authors:  Lu Bai; Xiaonan Zhang; Maya Kozlowski; Weixia Li; Min Wu; Jiangxia Liu; Liang Chen; Jiming Zhang; Yuxian Huang; Zhenghong Yuan
Journal:  J Virol       Date:  2018-11-27       Impact factor: 5.103
  1 in total

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