Literature DB >> 4689830

Plasma digoxin concentration in children with heart failure.

J E Cree, D J Coltart, M R Howard.   

Abstract

A dosage schedule for digoxin medication is presented which has proved effective and safe in children of different ages with heart failure due to a variety of cardiac conditions. The plasma digoxin concentrations during maintenance therapy, using this schedule, agree closely with previously reported therapeutic adult plasma concentrations, though the results do not exclude the efficiency and safety of higher doses. A twice-daily dosage regimen is suggested.

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Year:  1973        PMID: 4689830      PMCID: PMC1588466          DOI: 10.1136/bmj.1.5851.443

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  5 in total

1.  Digoxin dosage in premature infants.

Authors:  O R LEVINE; S BLUMENTHAL
Journal:  Pediatrics       Date:  1962-01       Impact factor: 7.124

2.  Effects of digoxin on systolic time intervals of neonates and infants.

Authors:  A M Levy; D M Leaman; J S Hanson
Journal:  Circulation       Date:  1972-10       Impact factor: 29.690

3.  Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay.

Authors:  T W Smith; V P Butler; E Haber
Journal:  N Engl J Med       Date:  1969-11-27       Impact factor: 91.245

4.  Plasma digoxin concentrations in patients with atrial fibrillation.

Authors:  D A Chamberlain; R J White; M R Howard; T W Smith
Journal:  Br Med J       Date:  1970-08-22

5.  Digitalis intoxication. A prospective clinical study with serum level correlations.

Authors:  G A Beller; T W Smith; W H Abelmann; E Haber; W B Hood
Journal:  N Engl J Med       Date:  1971-05-06       Impact factor: 91.245

  5 in total
  4 in total

1.  Dose of digoxin and age of child.

Authors:  B S Doshi; K C Vijayaraghavan; D Ajit; B L Chauhan; Y K Amdekar; R D Kulkarni
Journal:  Indian J Pediatr       Date:  1987 Mar-Apr       Impact factor: 1.967

2.  Digoxin dosage schedules for neonates and infants based on pharmacokinetic considerations.

Authors:  L Nyberg; G Wettrell
Journal:  Clin Pharmacokinet       Date:  1978 Nov-Dec       Impact factor: 6.447

Review 3.  Clinical pharmacokinetics of digoxin in infants.

Authors:  G Wettrell; K E Andersson
Journal:  Clin Pharmacokinet       Date:  1977 Jan-Feb       Impact factor: 6.447

4.  Steady state serum concentrations and renal clearance of digoxin in neonates, infants and children.

Authors:  H Halkin; M Radomsky; P Millman; S Almog; L Blieden; H Boichis
Journal:  Eur J Clin Pharmacol       Date:  1978-05-17       Impact factor: 2.953

  4 in total

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