| Literature DB >> 4685707 |
Abstract
TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient's thymus; the differentiated TL(+) cells then evoke production of TL antibody.Entities:
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Year: 1973 PMID: 4685707 PMCID: PMC2139483 DOI: 10.1084/jem.137.2.533
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307