Literature DB >> 4685043

Cholesterol: vitamin C controls its transformation to bile acids.

E Ginter.   

Abstract

Cholesterol accumulates in the blood serum and in the liver of guinea pigs with chronic latent vitamin C deficiency. The reason for this is the decreased rate of transformation of cholesterol to bile acids in the liver of animals deficient in vitamin C. A significant direct correlation exists between the vitamin C concentration in the liver and the rate of cholesterol transformation to bile acids.

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Year:  1973        PMID: 4685043     DOI: 10.1126/science.179.4074.702

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  15 in total

1.  Reduction of gallstone formation by ascorbic acid in hamsters.

Authors:  E Ginter; L Mikus
Journal:  Experientia       Date:  1977-06-15

Review 2.  Breath-analysis tests in gastroenterology.

Authors:  A Newman
Journal:  Gut       Date:  1974-04       Impact factor: 23.059

3.  Effects of dietary cholesterol upon bile acid metabolism in guinea pig.

Authors:  H Hansma; R Ostwald
Journal:  Lipids       Date:  1974-10       Impact factor: 1.880

4.  Influence of vitamin C on hydroxylation and side chain oxidation of cholesterol in vitro.

Authors:  D Kritchevsky; S A Tepper; J A Story
Journal:  Lipids       Date:  1973-08       Impact factor: 1.880

5.  Serum triglycerides and post-heparin lipolytic activity in guinea-pigs with latent vitamin C deficiency.

Authors:  P Bobek; E Ginter
Journal:  Experientia       Date:  1978-12-15

6.  Vitamin C and gallstone formation: a preliminary report.

Authors:  S A Jenkins
Journal:  Experientia       Date:  1977-12-15

7.  Effect of ascorbic acid on arylsulfatase activities and sulfated proteoglycan metabolism in chondrocyte cultures.

Authors:  E R Schwartz; L Adamy
Journal:  J Clin Invest       Date:  1977-07       Impact factor: 14.808

8.  Serum ascorbic acid and other correlates of gallbladder disease among US adults.

Authors:  J A Simon; E S Hudes
Journal:  Am J Public Health       Date:  1998-08       Impact factor: 9.308

9.  Ascorbic acid deficiency in liver disease.

Authors:  A D Beattie; S Sherlock
Journal:  Gut       Date:  1976-08       Impact factor: 23.059

10.  Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population.

Authors:  Thomas Walcher; Mark M Haenle; Martina Kron; Birgit Hay; Richard A Mason; Daniel Walcher; Gerald Steinbach; Peter Kern; Isolde Piechotowski; Guido Adler; Bernhard O Boehm; Wolfgang Koenig; Wolfgang Kratzer
Journal:  BMC Gastroenterol       Date:  2009-10-08       Impact factor: 3.067

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