Literature DB >> 468382

Toxin-neutralizing effect of antibody against subtilisin-digested tetanus toxin.

H Sato, A Ito, Y Yamakawa, R Murata.   

Abstract

A form of systemic tetanus with atypical symptoms was observed in mice injected in the left thigh with a mixture of tetanus toxin and antibody produced in guinea pigs against a fragment of toxin obtained from a subtilisin digest of the crystallized toxin. The mice did not show typical symptoms of the local tetanus such as convulsions or spastic paralysis of the injected limb.

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Year:  1979        PMID： 468382      PMCID： PMC414401          DOI： 10.1128/iai.24.3.958-961.1979

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  7 in total

1.  Studies on tetanus antitoxins. II. Demonstration of at least four antitoxins of different specificity in antitoxic sera.

Authors:  J Nagel; H Cohen
Journal:  J Immunol       Date:  1973-05       Impact factor: 5.422

2.  Ganglioside as a prophylactic agent in experimental tetanus in mice.

Authors:  J Mellanby; H Mellanby; D Pope; W E Van Heyningen
Journal:  J Gen Microbiol       Date:  1968-12

3.  Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.

Authors:  T B Helting; H J Ronneberger; R Vollerthun; V Neubauer
Journal:  J Biol Chem       Date:  1978-01-10       Impact factor: 5.157

4.  Isolation and purification of two antigenically active, "complimentary" polypeptide fragments of tetanus neurotoxin.

Authors:  M Matsuda; M Yoneda
Journal:  Infect Immun       Date:  1975-11       Impact factor: 3.441

5.  Structure of tetanus toxin. II. Toxin binding to ganglioside.

Authors:  T B Helting; O Zwisler; H Wiegandt
Journal:  J Biol Chem       Date:  1977-01-10       Impact factor: 5.157

6.  Antigenic substructure of tetanus neurotoxin.

Authors:  M Matsuda; M Yoneda
Journal:  Biochem Biophys Res Commun       Date:  1977-07-11       Impact factor: 3.575

7.  Structure of tetanus toxin. I. Breakdown of the toxin molecule and discrimination between polypeptide fragments.

Authors:  T B Helting; O Zwisler
Journal:  J Biol Chem       Date:  1977-01-10       Impact factor: 5.157
  7 in total
  1 in total

1.  A review of the molecular structure of tetanus toxin.

Authors:  J P Robinson; J H Hash
Journal:  Mol Cell Biochem       Date:  1982-10-01       Impact factor: 3.396
  1 in total

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