Literature DB >> 4682691

From Asia securinine--a central nervous stimulant is used in treatment of amytrophic lateral sclerosis.

R Copperman, G Copperman, A Der Marderosian.   

Abstract

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Year:  1973        PMID： 4682691

Source DB:  PubMed          Journal:  Pa Med        ISSN： 0031-4595


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  6 in total

1.  L-securinine inhibits the proliferation of A549 lung cancer cells and promotes DKK1 promoter methylation.

Authors:  Shuwen Han; Xi Yang; Yuefen Pan; Quan Qi; Junjun Shen; Huifen Fang; Zhaoning Ji
Journal:  Oncol Lett       Date:  2017-08-01       Impact factor: 2.967

2.  Synthesis and Antiproliferative and Metabolic Evaluations of Novel Securinine Derivatives.

Authors:  Marc Perez; Tahar Ayad; Philippe Maillos; Valérie Poughon; Jacques Fahy; Virginie Ratovelomanana-Vidal
Journal:  ACS Med Chem Lett       Date:  2016-02-02       Impact factor: 4.345

3.  Securinine, a myeloid differentiation agent with therapeutic potential for AML.

Authors:  Kalpana Gupta; Amitabha Chakrabarti; Sonia Rana; Ritu Ramdeo; Bryan L Roth; Munna L Agarwal; William Tse; Mukesh K Agarwal; David N Wald
Journal:  PLoS One       Date:  2011-06-24       Impact factor: 3.240

4.  Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson's Disease.

Authors:  Dmitri Leonoudakis; Anand Rane; Suzanne Angeli; Gordon J Lithgow; Julie K Andersen; Shankar J Chinta
Journal:  Mediators Inflamm       Date:  2017-04-04       Impact factor: 4.711

5.  Predicting therapeutic drugs for hepatocellular carcinoma based on tissue-specific pathways.

Authors:  Liang Yu; Meng Wang; Yang Yang; Fengdan Xu; Xu Zhang; Fei Xie; Lin Gao; Xiangzhi Li
Journal:  PLoS Comput Biol       Date:  2021-02-09       Impact factor: 4.475

Review 6.  Unique indolizidine alkaloid securinine is a promising scaffold for the development of neuroprotective and antitumor drugs.

Authors:  Sergey Klochkov; Margarita Neganova
Journal:  RSC Adv       Date:  2021-05-26       Impact factor: 4.036
  6 in total

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