Literature DB >> 4682133

Photoreactivation of ultraviolet-induced chromosomal aberrations.

H G Griggs, M A Bender.   

Abstract

Ultraviolet induces only chromatid-type aberrations in synchronized G(1) V-79 Chinese hamster and A8W243 Xenopus tissue culture cells. Posttreatment with white light prevents expression of most potential aberrations in the A8 toad cell, which possesses a photoreactivation enzyme. We conclude that the major ultraviolet-induced DNA lesion leading to chromosomal aberrations is the pyrimidine dimer.

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Year:  1973        PMID: 4682133     DOI: 10.1126/science.179.4068.86

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

1.  The fate of U.V.-induced lesions affecting SCEs, chromosome abberrations and survival of CHO cells arrested by deprivation of arginine.

Authors:  W D MacRae; E A MacKinnon; H F Stich
Journal:  Chromosoma       Date:  1979-04-05       Impact factor: 4.316

2.  Isolabelling is a radiation-induced phenomenon.

Authors:  N V Luchnik; N A Porjadkova
Journal:  Chromosoma       Date:  1977-08-18       Impact factor: 4.316

3.  Photoreactivation of UV induced cell killing, chromosome aberrations, sister chromatid exchanges, mutations and pyrimidine dimers in Xenopus laevis fibroblasts.

Authors:  A A van Zeeland; A T Natarajan; E A Verdegaal-Immerzeel; A R Filon
Journal:  Mol Gen Genet       Date:  1980

4.  Delayed formation of chromosome aberrations in mouse pachytene spermatocytes treated with triethylenemelamine (TEM).

Authors:  W M Generoso; M Krishna; R E Sotomayor; N L Cacheiro
Journal:  Genetics       Date:  1977-01       Impact factor: 4.562

5.  Mutagen specificity in the induction of chromosomal aberrations in somatic cells of Drosophila melanogaster.

Authors:  S Pimpinelli; D Pignone; G Santini; M Gatti; G Olivieri
Journal:  Genetics       Date:  1977-02       Impact factor: 4.562

6.  The production of chromosome aberrations in various mammalian cells by triethylenemelamine.

Authors:  H E Luippold; P C Gooch; J G Brewen
Journal:  Genetics       Date:  1978-02       Impact factor: 4.562

  6 in total

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