Literature DB >> 46781

Biochemical characterization of putative subviral particulates from human malignant breast tumors.

R Michalides, S Spiegelman, J Schlom.   

Abstract

Particulates with the properties of cores and/or ribonucleoproteins of RNA tumor viruses have been isolated from Sterox-SL-treated fractions of murine and human mammary adenocarcinomas. These particulates have an RNA-directed DNA polymerase, a 60 to 70 S RNA, and a density of 1.26 g/ml or greater in sucrose equilibrium density gradients. Their uniquely higher densities lead to banding in regions comparatively free of cellular contaminants. These circumstances minimize some of the technical complications of performing the simultaneous detection assay in the presence of cell debris.

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Year:  1975        PMID： 46781

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  9 in total

1.  Detection in human breast carcinomas of an antigen immunologically related to a group-specific antigen of mouse mammary tumor virus.

Authors:  R Mesa-Tejada; I Keydar; M Ramanarayanan; T Ohno; C Fenoglio; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

2.  A compendium of the mouse mammary tumor biologist: from the initial observations in the house mouse to the development of genetically engineered mice.

Authors:  Robert D Cardiff; Nicholas Kenney
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-06-01       Impact factor: 10.005

3.  Purification of RNA-instructed DNA polymerase from human leukemic spleens.

Authors:  S S Witkin; T Ohno; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

4.  Properties of retrovirus-like particles produced by a human breast carcinoma cell line: immunological relationship with mouse mammary tumor virus proteins.

Authors:  I Keydar; T Ohno; R Nayak; R Sweet; F Simoni; F Weiss; S Karby; R Mesa-Tejada; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

5.  Antigenic relatedness of the DNA polymerase of human breast cancer particles to the enzyme of the Mason-Pfizer monkey virus.

Authors:  T Ohno; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-05       Impact factor: 11.205

6.  Purification and characterization of the DNA polymerase of human breast cancer particles.

Authors:  T Ohno; R W Sweet; D Dejak; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

7.  Detection and identification of mouse mammary tumor virus-like DNA sequences in blood and breast tissues of breast cancer patients.

Authors:  Wasifa Naushad; Talha Bin Rahat; Miriam Kathleen Gomez; Muhammad Taimoor Ashiq; Muhammad Younas; Hajra Sadia
Journal:  Tumour Biol       Date:  2014-05-19

Review 8.  Integration of maternal genome into the neonate genome through breast milk mRNA transcripts and reverse transcriptase.

Authors:  M Kemal Irmak; Yesim Oztas; Emin Oztas
Journal:  Theor Biol Med Model       Date:  2012-06-07       Impact factor: 2.432

Review 9.  The Viral Origin of Human Breast Cancer: From the Mouse Mammary Tumor Virus (MMTV) to the Human Betaretrovirus (HBRV).

Authors:  Generoso Bevilacqua
Journal:  Viruses       Date:  2022-08-01       Impact factor: 5.818
  9 in total

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