| Literature DB >> 467506 |
J A Garcia-Sevilla, M L Dubocovich, S Z Langer.
Abstract
Antiotensin II facilitated in a concentration-dependent manner the potassium-evoked 3H-noradrenaline over-flow from the rabbit hypothalamus. This effect which is probably mediated through presynaptic angiotensin facilitatory receptors on noradrenergic nerve terminals was blocked by the specific angiotensin receptor antagonist, saralasin. These results demonstrate that angiotensin II also facilitates the stimulation-evoked release of noradrenaline in the central nervous system.Entities:
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Year: 1979 PMID: 467506 DOI: 10.1016/0014-2999(79)90449-7
Source DB: PubMed Journal: Eur J Pharmacol ISSN: 0014-2999 Impact factor: 4.432