Literature DB >> 466443

Regional distribution of methionine-enkephalin- and beta-endorphin-like immunoreactivity in human brain and pituitary.

C Gramsch, V Höllt, P Mehraein, A Pasi, A Herz.   

Abstract

Concentrations of methionine-enkephalin- (Met-enkephalin) and beta-endorphin-like immunoreactivities were determined in 33 areas of human brain and pituitary using highly sensitive radioimmunoassays in combination with affinity chromatography for the purification of beta-endorphin. It was found that they have quite different distribution patterns, suggesting the existence of both endorphins in independent systems in the central nervous system. Determination of Met-enkephalin and beta-endorphin immunoreactivities in chronic alcoholics and opiate-dependent subjects revealed no gross changes in comparison to the normal subjects.

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Year:  1979        PMID： 466443     DOI： 10.1016/0006-8993(79)90332-9

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  12 in total

1.  Electrospray mass spectrometry for the analysis of opioid peptides and for the quantification of endogenous methionine enkephalin and β-endorphin.

Authors:  C Dass; J J Kusmierz; D M Desiderio; S A Jarvis; B N Green
Journal:  J Am Soc Mass Spectrom       Date:  1991-04       Impact factor: 3.109

2.  Release of met-enkephalin and its modulation through acetylcholine receptors in the rabbit superior colliculus.

Authors:  R B Illing; K E Nikolarakis; T Wichmann; W B Spatz; K Starke
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

3.  Electrical stimulation in vivo increases the expression of proenkephalin mRNA and decreases the expression of prodynorphin mRNA in rat hippocampal granule cells.

Authors:  B J Morris; K J Feasey; G ten Bruggencate; A Herz; V Höllt
Journal:  Proc Natl Acad Sci U S A       Date:  1988-05       Impact factor: 11.205

4.  Striato-nigral dynorphin and substance P pathways in the rat. I. Biochemical and immunohistochemical studies.

Authors:  I Christensson-Nylander; M Herrera-Marschitz; W Staines; T Hökfelt; L Terenius; U Ungerstedt; C Cuello; W H Oertel; M Goldstein
Journal:  Exp Brain Res       Date:  1986       Impact factor: 1.972

Review 5.  Hypothalamic neuropeptide signaling in alcohol addiction.

Authors:  Jessica R Barson; Sarah F Leibowitz
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2015-02-14       Impact factor: 5.067

6.  Relationship of the central ACTH-immunoreactive opiocortin system to the median eminence and the pituitary gland of the rat.

Authors:  K M Knigge; S A Joseph
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

7.  Presynaptic modulation of synaptic transmission by opioid receptor in rat subthalamic nucleus in vitro.

Authors:  Ke-Zhong Shen; Steven W Johnson
Journal:  J Physiol       Date:  2002-05-15       Impact factor: 5.182

8.  Immunoreactive beta-endorphin and adrenocorticotropin in human cerebrospinal fluid.

Authors:  K Nakao; S Oki; I Tanaka; K Horii; Y Nakai; T Furui; M Fukushima; A Kuwayama; N Kageyama; H Imura
Journal:  J Clin Invest       Date:  1980-12       Impact factor: 14.808

9.  Methionine-enkephalin and substance P in the basal ganglia of normals, Parkinson patients, Huntington patients, and schizophrenics. A qualitative immunohistochemical study.

Authors:  M Zech; B Bogerts
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

10.  Do Resting Plasma β-Endorphin Levels Predict Responses to Opioid Analgesics?

Authors:  Stephen Bruehl; John W Burns; Rajnish Gupta; Asokumar Buvanendran; Melissa Chont; Daria Orlowska; Erik Schuster; Christopher R France
Journal:  Clin J Pain       Date:  2017-01       Impact factor: 3.442
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