Experimental oral immunization with L-forms of Vibrio cholerae.

It has been found that oral administration of lysates of L-forms of Vibrio cholerae are antigenic and capable of eliciting an early and high coproantibody response. The L-forms of V. cholerae did not produce any booster effect. Coproantibody rise persists to significant levels even six weeks after oral immunization. L-form lysates of V. cholerae also produce a considerable rise of circulating antibodies and these persist in significantly high titers up to six weeks.