Literature DB >> 4655272

A new example of a morphine-sensitive neuro-effector junction: adrenergic transmission in the mouse vas deferens.

G Henderson, J Hughes, H W Kosterlitz.   

Abstract

The isolated mouse vas deferens possesses an adrenergic excitatory motor innervation which can be inhibited by low concentrations of morphine (ID50=0.5 muM). This effect of morphine is mediated by specific receptors which are blocked by naloxone. Activation of the morphine receptors inhibits noradrenaline release. It is concluded that adrenergic neurotransmission in the mouse vas deferens differs in some important way from that at the more common, morphine-insensitive, adrenergic junctions.

Entities:  

Mesh：

Substances：

Year:  1972        PMID： 4655272      PMCID： PMC1666368          DOI： 10.1111/j.1476-5381.1972.tb06901.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  6 in total

1.  The action of morphine on the superior cervical ganglion and on the nictitating membrane of the cat.

Authors:  U TRENDELENBURG
Journal:  Br J Pharmacol Chemother       Date:  1957-03

2.  3 H-noradrenaline release and mechanical response in the field stimulated mouse vas deferens.

Authors:  L O Farnebo; T Malamfors
Journal:  Acta Physiol Scand Suppl       Date:  1971

3.  The effects of hexamethonium, morphine and adrenaline on the output of acetylcholine from the myenteric plexus-longitudinal muscle preparation of the ileum.

Authors:  R Greenberg; H W Kosterlitz; A A Waterfield
Journal:  Br J Pharmacol       Date:  1970-11       Impact factor: 8.739

4.  The action of morphine and related substances on contraction and on acetylcholine output of coaxially stimulated guinea-pig ileum.

Authors:  W D PATON
Journal:  Br J Pharmacol Chemother       Date:  1957-03

5.  Effect of morphine on some sympathetically innervated effectors.

Authors:  A B CAIRNIE; H W KOSTERLITZ; D W TAYLOR
Journal:  Br J Pharmacol Chemother       Date:  1961-12

6.  Evaluation of mechanisms controlling the release and inactivation of the adrenergic transmitter in the rabbit portal vein and vas deferens.

Authors:  J Hughes
Journal:  Br J Pharmacol       Date:  1972-03       Impact factor: 8.739
  6 in total
  71 in total

1.  Effect of chronic morphine treatment on alpha(2)-adrenoceptor mediated autoinhibition of transmitter release from sympathetic varicosities of the mouse vas deferens.

Authors:  S Karunanithi; N A Lavidis
Journal:  Br J Pharmacol       Date:  2001-01       Impact factor: 8.739

2.  Bifunctional μ/δ opioid peptides: variation of the type and length of the linker connecting the two components.

Authors:  Jinguo Ding; Carole Lemieux; Nga N Chung; Peter W Schiller
Journal:  Chem Biol Drug Des       Date:  2012-01-04       Impact factor: 2.817

3.  Animal and molecular pharmacology of mixed agonist-antagonist analgesic drugs.

Authors:  M J Rance
Journal:  Br J Clin Pharmacol       Date:  1979       Impact factor: 4.335

4.  An examination of the putative sigma-receptor in the mouse isolated vas deferens.

Authors:  C Kennedy; G Henderson
Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

5.  Effects of narcotic analgesics and their antagonists on the rabbit isolated heart and its adrenergic nerves.

Authors:  H Montel; K Starke
Journal:  Br J Pharmacol       Date:  1973-12       Impact factor: 8.739

6.  The distribution of adrenoceptors and other drug receptors between the two ends of the rat vas deferens as revealed by selective agonists and antagonists.

Authors:  A MacDonald; J C McGrath
Journal:  Br J Pharmacol       Date:  1980       Impact factor: 8.739

7.  Genotype dependent response of morphine and methionine-enkephalin on the electrically induced contractions of the mouse vas deferens.

Authors:  F Berti; F Bruno; C Omini; G Racagni
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-10       Impact factor: 3.000

8.  Influence of morphine and naloxone on the release of noradrenaline from rat cerebellar cortex slices.

Authors:  H Montel; K Starke; H D Taube
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

9.  Opiate antagonistic properties of an octapeptide somatostatin analog.

Authors:  R Maurer; B H Gaehwiler; H H Buescher; R C Hill; D Roemer
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

10.  The effects of morphine on the release of noradrenaline from the mouse vas deferens.

Authors:  G Henderson; J Hughes
Journal:  Br J Pharmacol       Date:  1976-08       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.