Literature DB >> 4646303

A rapid micro-method for the screening and measurement of barbiturates and related compounds in plasma by gas-liquid chromatography.

R J Flanagan, G Withers.   

Abstract

A rapid gas-chromatographic method has been developed for the determination of butobarbitone, amylobarbitone, hexabarbitone, pentobarbitone, quinalbarbitone, phenobarbitone glutethimide, and methaqualone in ;finger-prick' samples of plasma. This has been applied to the analysis of some of these drugs in plasma taken from patients after therapeutic dosage and over-dosage.

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Year:  1972        PMID： 4646303      PMCID： PMC477544          DOI： 10.1136/jcp.25.10.899

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  7 in total

1.  QUANTITATIVE ESTIMATION AND IDENTIFICATION OF BARBITURATES IN BLOOD IN EMERGENCY CASES.

Authors:  H V STREET; C MCMARTIN
Journal:  Nature       Date:  1963-08-03       Impact factor: 49.962

2.  [RECOGNITION AND DETERMINATION OF BARBITURATES IN THE BLOOD USING GAS CHROMATOGRAPHY].

Authors:  J F REITH; R F VAN DER HEIDE; R F ZWAAL
Journal:  Pharm Weekbl       Date:  1965-02-12

3.  The determination of barbiturates and some related drugs by gas chromatography.

Authors:  H Leach; P A Toseland
Journal:  Clin Chim Acta       Date:  1968-05       Impact factor: 3.786

4.  Rapid identification and quantitative determination of barbiturates and glutethimide in blood by gas-liquid chromatography.

Authors:  J MacGee
Journal:  Clin Chem       Date:  1971-07       Impact factor: 8.327

5.  Rapid micromethod for gas chromatographic determination of blood barbiturates.

Authors:  M W Anders
Journal:  Anal Chem       Date:  1966-12       Impact factor: 6.986

6.  Gas-liquid chromatography of submicrogram amounts of drugs. II. Analysis of barbiturates and related drugs in biological media.

Authors:  C McMartin; H V Street
Journal:  J Chromatogr       Date:  1966-07

7.  Gas chromatographic determination of methaqualone, 2-methyl-3-o-tolyl-4(3H)-quinazolinone, at therapeutic levels in human plasma.

Authors:  D J Berry
Journal:  J Chromatogr       Date:  1969-06-03
  7 in total
  6 in total

1.  Effects of the calcium channel activator Bay K 8644 on general anaesthetic potency in mice.

Authors:  S J Dolin; M J Halsey; H J Little
Journal:  Br J Pharmacol       Date:  1988-06       Impact factor: 8.739

2.  Comparison of haemoperfusion and haemodialysis in the therapy of barbiturate intoxication in dogs.

Authors:  R K Medd; B Widdop; R A Braithwaite; A J Rees; R Goulding
Journal:  Arch Toxikol       Date:  1973

3.  Fatal self-poisoning with Dettol.

Authors:  D Meek; R Gabriel; D M Piercy
Journal:  Postgrad Med J       Date:  1977-04       Impact factor: 2.401

4.  Use of charcoal haemoperfusion in the management of severely poisoned patients.

Authors:  J A Vale; A J Rees; B Widdop; R Goulding
Journal:  Br Med J       Date:  1975-01-04

5.  Studies with activated charcoal in the treatment of drug overdosage using the pig as an animal model.

Authors:  D J Lipscomb; B Widdop
Journal:  Arch Toxicol       Date:  1975-09-05       Impact factor: 5.153

6.  Experimental drug intoxication: treatment with charcoal haemoperfusion.

Authors:  B Widdop; R K Medd; R A Braithwaite; A J Rees; R Goulding
Journal:  Arch Toxicol       Date:  1975-09-05       Impact factor: 5.153
  6 in total

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