Literature DB >> 463497

Spindle-shaped appendages of IIIab-pyramids filled with lipofuscin: a striking pathological change of the senescent human isocortex.

H Braak.   

Abstract

Brains from 30 mentally normal men, ranging in age from 18--90 years, were studied to assess the occurrence and development of lipofuscin-filled spindle-shaped appendages of pyramidal cells of the isocortex; these can generally be encountered in the senescent brain within layer IIIab. The number of pigmented spindles was determined in a circumscribed part of prefrontal area revealing a close association of this conspicuous pathological alteration with growing age.

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Year:  1979        PMID： 463497     DOI： 10.1007/bf00690844

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  32 in total

1.  Alzheimer's neurofibrillary changes. A topographic study.

Authors:  A HIRANO; H M ZIMMERMAN
Journal:  Arch Neurol       Date:  1962-09

2.  Granulovacuolar degeneration in the ageing brain and in dementia.

Authors:  M J Ball; P Lo
Journal:  J Neuropathol Exp Neurol       Date:  1977-05       Impact factor: 3.685

3.  [Nuclei of the human brain stem. V. The dorsal glossopharyngeus-vagus-complex].

Authors:  H Braak
Journal:  Z Zellforsch Mikrosk Anat       Date:  1972

4.  Observations on the brains of demented old people.

Authors:  B E Tomlinson; G Blessed; M Roth
Journal:  J Neurol Sci       Date:  1970-09       Impact factor: 3.181

5.  [Staining the Nissl bodies in 4--10 microns thick Araldite sections with an area of about 2x2 cm (author's transl)].

Authors:  E Braak
Journal:  Microsc Acta       Date:  1976-09

6.  On pigment-loaded stellate cells within layer II and III of the human isocortex.

Authors:  H Braak
Journal:  Cell Tissue Res       Date:  1974       Impact factor: 5.249

7.  Cell frequencies in the human inferior olivary nuclear complex.

Authors:  F Moatamed
Journal:  J Comp Neurol       Date:  1966-09       Impact factor: 3.215

8.  The relationship between lipofuscin pigment and ageing in the human nervous system.

Authors:  D M Mann; P O Yates; J E Stamp
Journal:  J Neurol Sci       Date:  1978-06       Impact factor: 3.181

9.  Fine structure of meganeurites and secondary growth processes in feline GM1-gangliosidosis.

Authors:  D P Purpura; G D Pappas; H J Baker
Journal:  Brain Res       Date:  1978-03-17       Impact factor: 3.252

10.  The limbic system in Alzheimer's disease. A neuropathologic investigation.

Authors:  M W Hopper; F S Vogel
Journal:  Am J Pathol       Date:  1976-10       Impact factor: 4.307
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  6 in total

1.  Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.

Authors:  E Bednarski; C E Ribak; G Lynch
Journal:  J Neurosci       Date:  1997-06-01       Impact factor: 6.167

Review 2.  Pathoarchitectonic pattern of iso- and allocortical lesions in juvenile and adult neuronal ceroid-lipofuscinosis.

Authors:  H Braak; E Braak
Journal:  J Inherit Metab Dis       Date:  1993       Impact factor: 4.982

3.  Loss of intracortical myelinated fibers: a distinctive age-related alteration in the human striate area.

Authors:  P Lintl; H Braak
Journal:  Acta Neuropathol       Date:  1983       Impact factor: 17.088

4.  Clinical and neuropathological aspects of long-term damage to the central nervous system after lithium medication.

Authors:  J Peiffer
Journal:  Arch Psychiatr Nervenkr (1970)       Date:  1981

Review 5.  Lysosomes and brain aging in mammals.

Authors:  Gary Lynch; Xiaoning Bi
Journal:  Neurochem Res       Date:  2003-11       Impact factor: 3.996

Review 6.  Impact of age-related neuroglial cell responses on hippocampal deterioration.

Authors:  Joseph O Ojo; Payam Rezaie; Paul L Gabbott; Michael G Stewart
Journal:  Front Aging Neurosci       Date:  2015-04-29       Impact factor: 5.750
  6 in total

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