| Literature DB >> 4629857 |
A J Kenyon, J E Gander, C Lopez, R A Good.
Abstract
Affinity chromatography was used to isolate the Aleutian disease virus of mink. Dissociation of the immunoadsorbent-virus complex with 0.75 molar sodium chloride and then with a glycine-hydrochloride gradient released infective particles resembling picornaviruses. The elution profile suggests that two different types of virus-antibody complexes are formed, one dissociated by sodium chloride and another that requires glycine-hydrochloride in addition to sodium chloride for release of virus.Entities:
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Year: 1973 PMID: 4629857 DOI: 10.1126/science.179.4069.187
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728