| Literature DB >> 4626639 |
Abstract
Isolated rat brain tubulin can be repolymerized in vitro in solutions containing adenosine triphosphate or guanosine triphosphate, magnesium ions, and a good calcium chelator. The extreme sensitivity of tubulin to calcium ions explains the failure of previous efforts to obtain polymerization and suggests a possible mechanism for regulation of microtubule polymerization in vivo.Entities:
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Year: 1972 PMID: 4626639 DOI: 10.1126/science.177.4054.1104
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728