Literature DB >> 4625529

Folate antagonists. 2. 2,4-Diamino-6-((aralkyl and (heterocyclic)methyl)amino)quinazolines, a novel class of antimetabolites of interest in drug-resistant malaria and Chagas' disease.

J Davoll, A M Johnson, H J Davies, O D Bird, J Clarke, E F Elslager.   

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Year:  1972        PMID： 4625529     DOI： 10.1021/jm00278a007

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  6 in total

1.  Antimalarial activities of new pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives.

Authors:  Jian Guan; Quan Zhang; Michael O'Neil; Nicanor Obaldia; Arba Ager; Lucia Gerena; Ai J Lin
Journal:  Antimicrob Agents Chemother       Date:  2005-12       Impact factor: 5.191

2.  New potential antimalarial agents: therapeutic-index evaluation of pyrroloquinazolinediamine and its prodrugs in a rat model of severe malaria.

Authors:  Lisa H Xie; Qigui Li; Ai J Lin; Kirsten Smith; Jing Zhang; Donald S Skillman
Journal:  Antimicrob Agents Chemother       Date:  2006-05       Impact factor: 5.191

3.  Antileishmanial activities of 2,4-diaminoquinazoline putative dihydrofolate reductase inhibitors.

Authors:  J D Berman; M King; N Edwards
Journal:  Antimicrob Agents Chemother       Date:  1989-11       Impact factor: 5.191

4.  Small molecules with antimicrobial activity against E. coli and P. aeruginosa identified by high-throughput screening.

Authors:  R De La Fuente; N D Sonawane; D Arumainayagam; A S Verkman
Journal:  Br J Pharmacol       Date:  2006-09-18       Impact factor: 8.739

5.  Pharmacokinetics, safety, and hydrolysis of oral pyrroloquinazolinediamines administered in single and multiple doses in rats.

Authors:  Qigui Li; Michael P Kozar; Todd W Shearer; Lisa H Xie; Ai J Lin; Kirsten S Smith; Yuanzheng Si; Lalaine Anova; Jing Zhang; Wilbur K Milhous; Donald R Skillman
Journal:  Antimicrob Agents Chemother       Date:  2007-06-11       Impact factor: 5.191

Review 6.  Prodrugs for the treatment of neglected diseases.

Authors:  Man Chin Chung; Elizabeth Igne Ferreira; Jean Leandro Santos; Jeanine Giarolla; Daniela Gonçales Rando; Adélia Emília Almeida; Priscila Longhin Bosquesi; Renato Farina Menegon; Lorena Blau
Journal:  Molecules       Date:  2007-03-19       Impact factor: 4.411
  6 in total

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