| Literature DB >> 462184 |
W J Schwartz, C B Smith, L Davidsen, H Savaki, L Sokoloff, M Mata, D J Fink, H Gainer.
Abstract
Physiological stimulation of the hypothalamo-neurohypophysial system by salt loading of rats resulted in a dramatically increased glucose utilization in the posterior pituitary but not in the paraventricular or supraoptic nuclei. The good correlation between glucose utilization and neural activity in the posterior pituitary (that is, nerve terminals) contrasted with the lack of correlation in the paraventricular and supraoptic nuclei (that is, the sites of the cell bodies of the same neurons). This difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.Entities:
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Year: 1979 PMID： 462184 DOI： 10.1126/science.462184
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728