Literature DB >> 4621798

Comparison of fluorescent antibody induced by rubella virus in vaccinee and convalescent individuals.

A Serafini, G C Cole, R G Brackett.   

Abstract

Specific rubella antibody detectable by indirect immunofluorescence developed in response to immunization with attenuated rubella vaccine, HPV-77, DK-12. Fluorescent antibody (FA) was found when vaccinee sera were reacted with antigens synthesized in three different acutely infected continuous cell lines: BHK-21, LLCMK-2, and RK-13. FA titers were high, and they correlated with antibody titers obtained by hemagglutination-inhibition tests. Levels of FA in vaccinated individuals were slightly lower than those found in persons recovered from natural rubella infections. Rubella FA persists a long time in convalescent individuals and appears to be maintained for at least 19 months in vaccinees.

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Year:  1972        PMID： 4621798      PMCID： PMC380278          DOI： 10.1128/am.23.1.66-71.1972

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  13 in total

1.  Recovery of rubella virus from army recruits.

Authors:  P D PARKMAN; E L BUESCHER; M S ARTENSTEIN
Journal:  Proc Soc Exp Biol Med       Date:  1962-10

2.  Fluorescent-antibody marker for vaccine-induced rubella antibodies.

Authors:  G C Brown; T P O'leary
Journal:  Infect Immun       Date:  1970-10       Impact factor: 3.441

3.  Complement-fixing and fluorescent antibody responses to an attenuated Rubella virus vaccine.

Authors:  N J Schmidt; E H Lennette
Journal:  Am J Epidemiol       Date:  1970-04       Impact factor: 4.897

4.  Serology of rubella. Virus neutralization, immunofluorescence in BHK21 cells, and hemagglutination inhibition.

Authors:  R Deibel; S M Cohen; C P Ducharme
Journal:  N Y State J Med       Date:  1968-06-01

5.  Synthesis of virus and macromolecules by rubella-infected cells.

Authors:  R Maes; A Vaheri; D Sedwick; S Plotkin
Journal:  Nature       Date:  1966-04-23       Impact factor: 49.962

6.  Attenuated rubella virus. I. Development and laboratory characterization.

Authors:  P D Parkman; H M Meyer; R L Kirschstein; H E Hopps
Journal:  N Engl J Med       Date:  1966-09-15       Impact factor: 91.245

7.  Rubella vaccine trials in adults and children. Comparison of three attenuated vaccines.

Authors:  J A Dudgeon; W C Marshall; C S Peckham
Journal:  Am J Dis Child       Date:  1969-08

8.  Micromorphological aspects of the development of rubella virus in BHK-21 cells.

Authors:  M R Edwards; S M Cohen; M Bruno; R Deibel
Journal:  J Virol       Date:  1969-04       Impact factor: 5.103

9.  Rubella-virus hemagglutination-inhibition test.

Authors:  G L Stewart; P D Parkman; H E Hopps; R D Douglas; J P Hamilton; H M Meyer
Journal:  N Engl J Med       Date:  1967-03-09       Impact factor: 91.245

10.  Enumeration of cell-infecting particles of Newcastle disease virus by the fluorescent antibody technique.

Authors:  E F WHEELOCK; I TAMM
Journal:  J Exp Med       Date:  1961-02-01       Impact factor: 14.307
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