Literature DB >> 462176

4-aminobutyrate:2-oxoglutarate aminotransferase in blood platelets.

H L White.   

Abstract

Platelet lysates obtained from blood of humans, dogs, and rats catalyzed the transamination of 4-aminobutyrate with 2-oxoglutarate as cosubstrate. Human platelet 4-aminobutyrate:2-oxoglutarate aminotransferase (36.5 +/- 3.2 picomoles per minute per milligram of platelet protein) resembled the brain enzyme in kinetic properties and in response to cofactors and inhibitors.

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Year:  1979        PMID: 462176     DOI: 10.1126/science.462176

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  9 in total

1.  GABA-transaminase activity in rat and human brain: regional, age and sex-related differences.

Authors:  F Sherif; L Eriksson; L Oreland
Journal:  J Neural Transm Gen Sect       Date:  1991

2.  4-Hydroxybutyric aciduria: a new inborn error of metabolism. III. Enzymology and inheritance.

Authors:  K M Gibson; I Jansen; L Sweetman; W L Nyhan; D Rating; C Jakobs; P Divry
Journal:  J Inherit Metab Dis       Date:  1984       Impact factor: 4.982

3.  Inhibition of the enzyme, GABA-aminotransferase in human platelets by vigabatrin, a potential antiepileptic drug.

Authors:  E Rimmer; G Kongola; A Richens
Journal:  Br J Clin Pharmacol       Date:  1988-02       Impact factor: 4.335

4.  Uptake of GABA and activity of GABA transaminase in blood platelets from children with absence epilepsy.

Authors:  Sirpa Rainesalo; Kai Eriksson; Pirjo Saransaari; Tapani Keränen
Journal:  Neurochem Res       Date:  2004-10       Impact factor: 3.996

5.  The effect of vigabatrin on brain and platelet GABA-transaminase activities.

Authors:  J B Bolton; E Rimmer; J Williams; A Richens
Journal:  Br J Clin Pharmacol       Date:  1989       Impact factor: 4.335

6.  Brain gamma-aminobutyrate transaminase and monoamine oxidase activities in suicide victims.

Authors:  F Sherif; J Marcusson; L Oreland
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  1991       Impact factor: 5.270

7.  Gamma-aminobutyrate aminotransferase activity in brains of schizophrenic patients.

Authors:  F Sherif; L Eriksson; L Oreland
Journal:  J Neural Transm Gen Sect       Date:  1992

Review 8.  gamma-Aminobutyric acid and cardiovascular function.

Authors:  F V DeFeudis
Journal:  Experientia       Date:  1983-08-15

9.  Demonstration of 4-aminobutyric acid aminotransferase deficiency in lymphocytes and lymphoblasts.

Authors:  K M Gibson; L Sweetman; W L Nyhan; I Jansen
Journal:  J Inherit Metab Dis       Date:  1985       Impact factor: 4.982

  9 in total

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