Literature DB >> 462131

Treatment of experimental Naegleria meningoencephalitis with a combination of amphotericin B and rifamycin.

Y H Thong, B Rowan-Kelly, A Ferrante.   

Abstract

The treatment of primary amoebic meningoencephalitis was examined using a mouse model. Rifamycin by itself was ineffective. However, a synergistic effect was observed when used in combination with amphotericin B. This finding may prove useful in the treatment of patients with primary amoebic meningoencephalitis, for which satisfactory treatment is currently unavailable.

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Year:  1979        PMID： 462131     DOI： 10.3109/inf.1979.11.issue-2.10

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN： 0036-5548


  3 in total

1.  Synergistic activities of azithromycin and amphotericin B against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis.

Authors:  Shannon M Soltow; George M Brenner
Journal:  Antimicrob Agents Chemother       Date:  2006-10-23       Impact factor: 5.191

2.  Activities of azithromycin and amphotericin B against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis.

Authors:  Shannon M Goswick; George M Brenner
Journal:  Antimicrob Agents Chemother       Date:  2003-02       Impact factor: 5.191

Review 3.  Drugs used for the treatment of cerebral and disseminated infections caused by free-living amoebae.

Authors:  Alexandre Taravaud; Zineb Fechtali-Moute; Philippe M Loiseau; Sébastien Pomel
Journal:  Clin Transl Sci       Date:  2021-03-01       Impact factor: 4.689
  3 in total

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