Literature DB >> 4616942

Subcellular localization of isoleucine-valine biosynthetic enzymes in yeast.

E D Ryan, G B Kohlhaw.   

Abstract

By using the method of stepwise homogenization of yeast spheroplast lysates employed previously with the leucine biosynthetic enzymes, it is shown that threonine deaminase, acetohydroxy acid synthase, Mg(2+)-dependent isomero-reductase, and dihydroxy acid dehydratase are particulate. Density gradient centrifugation and the behavior of marker enzymes suggest that all of the above enzymes of the isoleucine-valine biosynthetic pathway are associated with the mitochondria.

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Year:  1974        PMID： 4616942      PMCID： PMC245821          DOI： 10.1128/jb.120.2.631-637.1974

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  19 in total

1.  Isoleucine and valine metabolism in Escherichia coli. IX. Utilization of acetolactate and acetohydroxybutyrate.

Authors:  H E UMBARGER; B BROWN; E J EYRING
Journal:  J Biol Chem       Date:  1960-05       Impact factor: 5.157

2.  In situ regulation of yeast citrate synthase. Absence of ATP inhibition observed in vitro.

Authors:  P D Weitzman; J K Hewson
Journal:  FEBS Lett       Date:  1973-10-15       Impact factor: 4.124

3.  Subcellular localization of the leucine biosynthetic enzymes in yeast.

Authors:  E D Ryan; J W Tracy; G B Kohlhaw
Journal:  J Bacteriol       Date:  1973-10       Impact factor: 3.490

4.  Formation of the yeast mitochondrial membrane. 1. Effects of inhibitors of protein synthesis on the kinetics of enzyme appearance during glucose derepression.

Authors:  I C Kim; D S Beattie
Journal:  Eur J Biochem       Date:  1973-07-16

5.  Assay of yeast enzymes in situ. A potential tool in regulation studies.

Authors:  R Serrano; J M Gancedo; C Gancedo
Journal:  Eur J Biochem       Date:  1973-05-02

6.  Control of acetohydroxy acid synthetase in Neurospora crassa.

Authors:  S Takenaka; H Kuwana
Journal:  J Biochem       Date:  1972-11       Impact factor: 3.387

7.  The regulation of isoleucine-valine biosynthesis in Saccharomyces cerevisiae. 2. Identification and characterization of mutants lacking the acetohydroxyacid synthetase.

Authors:  P T Magee; H Robichon-Szulmajster
Journal:  Eur J Biochem       Date:  1968-02

8.  An acetohydroxy acid synthetase from Neurospora crassa.

Authors:  H Kuwana; D F Caroline; R W Harding; R P Wagner
Journal:  Arch Biochem Biophys       Date:  1968-10       Impact factor: 4.013

9.  Threonine deaminase from Bacillus subtilis. I. Purification of the enzyme.

Authors:  G W Hatfield; H E Umbarger
Journal:  J Biol Chem       Date:  1970-04-10       Impact factor: 5.157

10.  Separation of mitochondrial membranes of Neurospora crassa. II. Submitochondrial localization of the isoleucine-valine biosynthetic pathway.

Authors:  W E Cassady; E H Leiter; A Bergquist; R P Wagner
Journal:  J Cell Biol       Date:  1972-04       Impact factor: 10.539
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  44 in total

1.  Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism.

Authors:  Ludmila V Roze; Anindya Chanda; Maris Laivenieks; Randolph M Beaudry; Katherine A Artymovich; Anna V Koptina; Deena W Awad; Dina Valeeva; Arthur D Jones; John E Linz
Journal:  BMC Biochem       Date:  2010-08-24       Impact factor: 4.059

2.  Chromosomal Integration and Expression of Two Bacterial alpha-Acetolactate Decarboxylase Genes in Brewer's Yeast.

Authors:  K Blomqvist; M L Suihko; J Knowles; M Penttilä
Journal:  Appl Environ Microbiol       Date:  1991-10       Impact factor: 4.792

3.  Characterization of Leucine Auxotrophs of the White Rot Basidiomycete Phanerochaete chrysosporium.

Authors:  T A Molskness; M Alic; M H Gold
Journal:  Appl Environ Microbiol       Date:  1986-06       Impact factor: 4.792

4.  Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes.

Authors:  J C Jauniaux; L A Urrestarazu; J M Wiame
Journal:  J Bacteriol       Date:  1978-03       Impact factor: 3.490

5.  Physiological implications of the substrate specificities of acetohydroxy acid synthases from varied organisms.

Authors:  N Gollop; B Damri; D M Chipman; Z Barak
Journal:  J Bacteriol       Date:  1990-06       Impact factor: 3.490

6.  Exogenous Valine Reduces Conversion of Leucine to 3-Methyl-1-Butanol in Saccharomyces cerevisiae.

Authors:  R Bigelis; P D Weir; R R Jones; H E Umbarger
Journal:  Appl Environ Microbiol       Date:  1983-02       Impact factor: 4.792

7.  Biological role of the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

Authors:  P Niederberger; G Miozzari; R Hütter
Journal:  Mol Cell Biol       Date:  1981-07       Impact factor: 4.272

8.  Cloning and molecular analysis of two different ILV5 genes from a brewing strain of Saccharomyces cerevisiae.

Authors:  Q Xie; A Jiménez
Journal:  Curr Genet       Date:  1994 Nov-Dec       Impact factor: 3.886

9.  Isolation and structure of an acetolactate synthase gene from Schizosaccharomyces pombe and complementation of the ilv2 mutation in Saccharomyces cerevisiae.

Authors:  F Bekkaoui; S A Nadin-Davis; W L Crosby
Journal:  Curr Genet       Date:  1993-12       Impact factor: 3.886

10.  Quantitative evaluation of yeast's requirement for glycerol formation in very high ethanol performance fed-batch process.

Authors:  Julien Pagliardini; Georg Hubmann; Carine Bideaux; Sandrine Alfenore; Elke Nevoigt; Stéphane E Guillouet
Journal:  Microb Cell Fact       Date:  2010-05-21       Impact factor: 5.328
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