Literature DB >> 459994

Glaucoma hypothesis: application of the law of Laplace.

K Szczudlowski.   

Abstract

The objective of the proposed research is to design a test for anticipating glaucoma damage. In this project, the author is utilizing a mathematical equation defined by Laplace's law as applied to a hollow organ. Eye wall stress should be evaluated concomitantly with the intraocular pressure, in order to define the susceptibility of the eye to develop glaucoma. The idea presented in this paper allows for better understanding of different factors responsible for the pathogenesis of open angle glaucoma, of low pressure glaucoma, and of ocular hypertension. It allows one to predict how a given eye will react to a given pressure, that is, whether damage will occur or not. It might answer the question whether to treat right away, or wait and follow. It explains the higher prevalence of glaucoma in myopic eyes. It outlines easy, noninvasive, inexpensive preventive measures, which do not require new and costly facilities. The next step, in further elaboration of this project, should probably be to evaluate the relationship between the ocular pulse and pressure curve. This will be discussed and presented in the future.

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Mesh:

Year:  1979        PMID: 459994     DOI: 10.1016/0306-9877(79)90114-2

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  4 in total

1.  The glaucoma suspect: differentiation of the future glaucomatous eye from the non-glaucomatous suspect eye. 1. Ultrasonic measurements and eye-wall stress.

Authors:  I A Chisholm; S M Drance; B C Chauhan
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1989       Impact factor: 3.117

2.  The role of eye size in its pressure and motility.

Authors:  Harry H Mark
Journal:  Clin Ophthalmol       Date:  2007-06

3.  Variability of serum oxidative stress biomarkers relative to biochemical data and clinical parameters of glaucoma patients.

Authors:  Kaya N Engin; Bülent Yemişci; Ulviye Yiğit; Ahmet Ağaçhan; Cihan Coşkun
Journal:  Mol Vis       Date:  2010-07-09       Impact factor: 2.367

4.  Glaucomatous Optic Neuropathy: The Dark Side of the Moon.

Authors:  Shahin Yazdani
Journal:  J Ophthalmic Vis Res       Date:  2021-04-29
  4 in total

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