Literature DB >> 4597726

Effect of isoprinosine against challenge with A(H3N2)-Hong Kong influenza virus in volunteers.

S Longley, R L Dunning, R H Waldman.   

Abstract

Volunteers were challenged with A(H(3)N(2))/Hong Kong/8/68 influenza virus while being given prophylaxis with either isoprinosine or placebo in a double-blind experiment. Isoprinosine, which had demonstrable antiviral activity in animal models, did not appear to protect humans from clinical influenza. The only beneficial effect of the drug observed was a slight, but significant, reduction in virus shedding.

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Year:  1973        PMID： 4597726      PMCID： PMC444443          DOI： 10.1128/AAC.3.4.506

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  4 in total

1.  Newly recognized myxoviruses from children with respiratory disease.

Authors:  R M CHANOCK; R H PARROTT; K COOK; B E ANDREWS; J A BELL; T REICHELDERFER; A Z KAPIKIAN; F M MASTROTA; R J HUEBNER
Journal:  N Engl J Med       Date:  1958-01-30       Impact factor: 91.245

2.  Isoprinosine: lack of antiviral activity in experimental model infections.

Authors:  L A Glasgow; G J Galasso
Journal:  J Infect Dis       Date:  1972-08       Impact factor: 5.226

3.  The antiviral activity of isoprinosine.

Authors:  P Gordon; E R Brown
Journal:  Can J Microbiol       Date:  1972-09       Impact factor: 2.419

4.  Effect of isoprinosine against influenza and some other viruses causing respiratory diseases.

Authors:  R L Muldoon; L Mezny; G G Jackson
Journal:  Antimicrob Agents Chemother       Date:  1972-09       Impact factor: 5.191
  4 in total
  9 in total

1.  Evaluation of isoprinosine in experimental human rhinovirus infection.

Authors:  D M Pachuta; Y Togo; R B Hornick; A R Schwartz; S Tominaga
Journal:  Antimicrob Agents Chemother       Date:  1974-04       Impact factor: 5.191

2.  Inosiplex for localized herpes zoster in childhood cancer patients: preliminary controlled study.

Authors:  S Feldman; F A Hayes; S Chaudhary; M Ossi
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

3.  Isoprinosine augmentation of phytohemagglutinin-induced lymphocyte proliferation.

Authors:  J W Hadden; E M Hadden; R G Coffey
Journal:  Infect Immun       Date:  1976-02       Impact factor: 3.441

Review 4.  Ribavirin and inosiplex: a review of their present status in viral diseases.

Authors:  T W Chang; R C Heel
Journal:  Drugs       Date:  1981-08       Impact factor: 9.546

5.  Immunosuppression during influenza virus infection.

Authors:  G B Kantzler; S F Lauteria; C L Cusumano; J D Lee; R Ganguly; R H Waldman
Journal:  Infect Immun       Date:  1974-11       Impact factor: 3.441

6.  Plaque inhibition assay for drug susceptibility testing of influenza viruses.

Authors:  F G Hayden; K M Cote; R G Douglas
Journal:  Antimicrob Agents Chemother       Date:  1980-05       Impact factor: 5.191

Review 7.  Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.

Authors:  D M Campoli-Richards; E M Sorkin; R C Heel
Journal:  Drugs       Date:  1986-11       Impact factor: 9.546

Review 8.  Battling COVID-19: using old weapons for a new enemy.

Authors:  Rohit Kumar; Nitin Gupta; Parul Kodan; Ankit Mittal; Manish Soneja; Naveet Wig
Journal:  Trop Dis Travel Med Vaccines       Date:  2020-05-20

Review 9.  Viral respiratory illnesses.

Authors:  L J Anderson; P A Patriarca; J C Hierholzer; G R Noble
Journal:  Med Clin North Am       Date:  1983-09       Impact factor: 5.456
  9 in total

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